European lyssaviruses: distribution, prevalence and implications for conservation.

S. L. Harris, S. M. Brookes, Gareth Jones, A. M. Hutson, Paul Adrian Racey, A. R. Fooks

    Research output: Contribution to journalArticle

    33 Citations (Scopus)

    Abstract

    Worldwide, there are more than 1100 species of the Order Chiroptera, 45 of which are present in Europe, and 16 in the UK. Bats are reservoirs of, or can be infected by, several viral diseases, including rabies virus strains (in the Lyssavirus genus). Within this genus are bat variants that have been recorded in Europe; European bat lyssavirus 1 (EBLV-1), European bat lyssavirus 2 (EBLV-2) and, four currently unclassified isolates. Since 1977, 783 cases of EBLVs (by isolation of viral RNA) have been recorded in Europe. EBLV-1 or EBLV-2 has been identified in 12 bat species, with over 95% of EBLV-1 infections identified in Eptesicus serotinus. EBLV-2 is associated with Myotis species (Myotis daubentonii and Myotis dasycneme). A programme of passive surveillance in the United Kingdom between 1987 and 2004 tested 4871 bats for lyssaviruses. Of these, four M. daubentonii (3.5796 of submitted M. daubentonii) were positive for EBLV-2. Potential bias in the passive surveillance includes possible over-representation of synanthropic species and regional biases caused by varying bat submission numbers from different parts of the UK. In 2003, active surveillance in the UK began, and has detected an antibody prevalence level of 1-5% of EBLV-2 in M. daubentonii (n = 350), and one bat with antibodies to EBLV-1 in E. serotinus (n = 52). No cases of live lyssavirus infection or lyssavirus viral RNA have been detected through active surveillance. Further research and monitoring regarding prevalence, transmission, pathogenesis and immunity is required to ensure that integrated bat conservation continues throughout Europe, whilst enabling informed policy decision regarding both human and wildlife health issues. (c) 2006 Elsevier Ltd. All rights reserved.

    Original languageEnglish
    Pages (from-to)193-210
    Number of pages17
    JournalBiological Conservation
    Volume131
    DOIs
    Publication statusPublished - 2006

    Keywords

    • disease
    • surveillance
    • European bat lyssavirus
    • rabies
    • zoonoses
    • conservation
    • RABIES-RELATED VIRUS
    • NEW-YORK-STATE
    • INSECTIVOROUS BATS
    • VAMPIRE BATS
    • FRUIT BATS
    • DAUBENTONS BAT
    • UNITED-STATES
    • PHYLOGENETIC-RELATIONSHIPS
    • PTEROPUS-POLIOCEPHALUS
    • TADARIDA-BRASILIENSIS

    Cite this

    Harris, S. L., Brookes, S. M., Jones, G., Hutson, A. M., Racey, P. A., & Fooks, A. R. (2006). European lyssaviruses: distribution, prevalence and implications for conservation. Biological Conservation, 131, 193-210. https://doi.org/10.1016/j.biocon.2006.04.006

    European lyssaviruses: distribution, prevalence and implications for conservation. / Harris, S. L.; Brookes, S. M.; Jones, Gareth; Hutson, A. M.; Racey, Paul Adrian; Fooks, A. R.

    In: Biological Conservation, Vol. 131, 2006, p. 193-210.

    Research output: Contribution to journalArticle

    Harris, SL, Brookes, SM, Jones, G, Hutson, AM, Racey, PA & Fooks, AR 2006, 'European lyssaviruses: distribution, prevalence and implications for conservation.', Biological Conservation, vol. 131, pp. 193-210. https://doi.org/10.1016/j.biocon.2006.04.006
    Harris, S. L. ; Brookes, S. M. ; Jones, Gareth ; Hutson, A. M. ; Racey, Paul Adrian ; Fooks, A. R. / European lyssaviruses: distribution, prevalence and implications for conservation. In: Biological Conservation. 2006 ; Vol. 131. pp. 193-210.
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    abstract = "Worldwide, there are more than 1100 species of the Order Chiroptera, 45 of which are present in Europe, and 16 in the UK. Bats are reservoirs of, or can be infected by, several viral diseases, including rabies virus strains (in the Lyssavirus genus). Within this genus are bat variants that have been recorded in Europe; European bat lyssavirus 1 (EBLV-1), European bat lyssavirus 2 (EBLV-2) and, four currently unclassified isolates. Since 1977, 783 cases of EBLVs (by isolation of viral RNA) have been recorded in Europe. EBLV-1 or EBLV-2 has been identified in 12 bat species, with over 95{\%} of EBLV-1 infections identified in Eptesicus serotinus. EBLV-2 is associated with Myotis species (Myotis daubentonii and Myotis dasycneme). A programme of passive surveillance in the United Kingdom between 1987 and 2004 tested 4871 bats for lyssaviruses. Of these, four M. daubentonii (3.5796 of submitted M. daubentonii) were positive for EBLV-2. Potential bias in the passive surveillance includes possible over-representation of synanthropic species and regional biases caused by varying bat submission numbers from different parts of the UK. In 2003, active surveillance in the UK began, and has detected an antibody prevalence level of 1-5{\%} of EBLV-2 in M. daubentonii (n = 350), and one bat with antibodies to EBLV-1 in E. serotinus (n = 52). No cases of live lyssavirus infection or lyssavirus viral RNA have been detected through active surveillance. Further research and monitoring regarding prevalence, transmission, pathogenesis and immunity is required to ensure that integrated bat conservation continues throughout Europe, whilst enabling informed policy decision regarding both human and wildlife health issues. (c) 2006 Elsevier Ltd. All rights reserved.",
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