Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

D McAteer, Fintan Wallis, G Couper, Murdoch Norton, Andrew Welch, Duff Bruce, Ken Park, Marianne Nicholson, Fiona Jane Gilbert, Peter Frederick Sharp

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.
Original languageEnglish
Pages (from-to)525-529
Number of pages5
JournalBritish Journal of Radiology
Volume72
Issue number858
Publication statusPublished - Jun 1999

Fingerprint

Deoxyglucose
Positron-Emission Tomography
Stomach
Carcinoma
Drug Therapy
Neoplasms
Liver
Esophageal Neoplasms
Palliative Care
Stomach Neoplasms
Biopsy

Cite this

McAteer, D., Wallis, F., Couper, G., Norton, M., Welch, A., Bruce, D., ... Sharp, P. F. (1999). Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma. British Journal of Radiology, 72(858), 525-529.

Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma. / McAteer, D; Wallis, Fintan; Couper, G; Norton, Murdoch; Welch, Andrew; Bruce, Duff; Park, Ken; Nicholson, Marianne; Gilbert, Fiona Jane; Sharp, Peter Frederick.

In: British Journal of Radiology, Vol. 72, No. 858, 06.1999, p. 525-529.

Research output: Contribution to journalArticle

McAteer, D, Wallis, F, Couper, G, Norton, M, Welch, A, Bruce, D, Park, K, Nicholson, M, Gilbert, FJ & Sharp, PF 1999, 'Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma', British Journal of Radiology, vol. 72, no. 858, pp. 525-529.
McAteer, D ; Wallis, Fintan ; Couper, G ; Norton, Murdoch ; Welch, Andrew ; Bruce, Duff ; Park, Ken ; Nicholson, Marianne ; Gilbert, Fiona Jane ; Sharp, Peter Frederick. / Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma. In: British Journal of Radiology. 1999 ; Vol. 72, No. 858. pp. 525-529.
@article{05103439f1724869af8b85590ea1029b,
title = "Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma",
abstract = "The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.",
author = "D McAteer and Fintan Wallis and G Couper and Murdoch Norton and Andrew Welch and Duff Bruce and Ken Park and Marianne Nicholson and Gilbert, {Fiona Jane} and Sharp, {Peter Frederick}",
year = "1999",
month = "6",
language = "English",
volume = "72",
pages = "525--529",
journal = "British Journal of Radiology",
issn = "0007-1285",
publisher = "British Institute of Radiology",
number = "858",

}

TY - JOUR

T1 - Evaluation of 18f-FDG Positron Emission Tomography in Gastric and Oesophageal Carcinoma

AU - McAteer, D

AU - Wallis, Fintan

AU - Couper, G

AU - Norton, Murdoch

AU - Welch, Andrew

AU - Bruce, Duff

AU - Park, Ken

AU - Nicholson, Marianne

AU - Gilbert, Fiona Jane

AU - Sharp, Peter Frederick

PY - 1999/6

Y1 - 1999/6

N2 - The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.

AB - The aim of this study was to evaluate 18F-fluoro-deoxyglucose (FDG) positron emission tomography (PET) in gastric and oesophageal carcinoma. 16 patients with biopsy proven oesophageal or gastric carcinoma had PET scans. Four patients had advanced disease and received palliative treatment. The remaining 12 patients were randomized to immediate surgery or neoadjuvant chemotherapy. Three patients had repeat PET scans following chemotherapy. PET detected the primary tumour in all cases including stage T1 lesions. Involved locoregional nodes (N1, N2) were not identified separately from the primary tumour. Semiquantitative analysis was performed in the form of tumour to liver activity ratios (TLR). In general, the TLR values were higher in the higher T stages, although there was only one case each of T1 and T2 lesions. PET scanning using 18F-FDG is a sensitive method for detecting primary oesophageal and gastric cancers but is limited in locoregional staging.

M3 - Article

VL - 72

SP - 525

EP - 529

JO - British Journal of Radiology

JF - British Journal of Radiology

SN - 0007-1285

IS - 858

ER -