Factors affecting adherence to treatment of psoriasis: comparing biologic therapy to other modalities

Sue Ann Chan, F Hussain, Linda G Lawson, Anthony Ormerod

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Objectives: This study evaluated self-reported patient adherence to different types of treatment in psoriasis and factors that affect adherence. Patients and methods: Patients attending a Dermatology Department for treatments of psoriasis completed a questionnaire about adherence to each of their therapies, Self-assessed Psoriasis Area and Severity Index (SAPASI) and Dermatology Life Quality Index (DLQI). Results: Hundred and six patients participated, 98 on topical treatments, 43 on oral systemic therapies, 39 on phototherapy and 29 were on biologic therapies. The overall rate of self-reported treatment adherence was 85.8%. There was a significant relationship between the types of treatment (topical, oral systemic, phototherapy and biologic therapy) and the number of combinations of treatments and adherence. Adherence ranked significantly better on biologic therapies 100%, followed by oral therapy 96%, phototherapy 93% and then topical therapy 75%. Being too busy, being fed up and cigarette smoking were associated with reduced adherence. About 56.8% of patients reported that messiness of treatment prevented them from adhering. Patients with mild psoriasis and those with DLQI of 5 or less adhered less to topical therapy. Conclusions: There is a significant relationship between the types of treatment (topical, oral systemic, phototherapy and biologic therapy) and the number of combinations of treatments and adherence.
Original languageEnglish
Pages (from-to)64-69
Number of pages6
JournalJournal of Dermatological Treatment
Volume24
Issue number1
Early online date1 Jul 2011
DOIs
Publication statusPublished - Feb 2013

Keywords

  • adherence
  • biologic therapy
  • phototherapy
  • psoriasis
  • topical therapy

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