Abstract
Background: There are an estimated 200 million people in China with dyslipidaemia. We sought to explore factors that influence compliance to treatment of dyslipidaemia, using a multi-centre sample in China.
Methods: Through review of medical notes and direct interviews at two points in time (2006 and 2007) of 2094 patients in 27 hospitals receiving lipid-lowering therapy since 2004, 1890 patients were recruited who had been on treatment for more than one year. Good compliance (GC) was defined as days taking lipid-lowering drugs/total days of follow-up ≥80%. Logistic regression models were used to assess factors associated with GC.
Results: In patients with one, two and three years of treatment respectively, GC was greater in those with higher versus lower medical insurance cover – odds ratios 2.8 (95%CI 2.2–3.7), 2.0 (1.5–2.7), 4.3 (2.3–8.1); in patients in province-level versus county-level hospitals–2.0 (1.5–2.6), 2.9 (2.0–4.1), 4.6 (1.8–12.0); in patients treated by non-cardiology physicians compared to cardiologists −1.7 (1.1–2.5), 2.0 (1.3–3.0), 4.0 (1.5–10.3) and in patients using a statin versus other forms of medication for dyslipidaemia −1.7 (1.2–2.2), 1.7 (1.2–2.3), 4.4 (2.3–8.5).
Conclusions: Better medical insurance cover, care in a province-level hospital rather than county-level hospital, treatment by a non-cardiologist and use of a statin were associated with better compliance to lipid-lowering treatment.
Methods: Through review of medical notes and direct interviews at two points in time (2006 and 2007) of 2094 patients in 27 hospitals receiving lipid-lowering therapy since 2004, 1890 patients were recruited who had been on treatment for more than one year. Good compliance (GC) was defined as days taking lipid-lowering drugs/total days of follow-up ≥80%. Logistic regression models were used to assess factors associated with GC.
Results: In patients with one, two and three years of treatment respectively, GC was greater in those with higher versus lower medical insurance cover – odds ratios 2.8 (95%CI 2.2–3.7), 2.0 (1.5–2.7), 4.3 (2.3–8.1); in patients in province-level versus county-level hospitals–2.0 (1.5–2.6), 2.9 (2.0–4.1), 4.6 (1.8–12.0); in patients treated by non-cardiology physicians compared to cardiologists −1.7 (1.1–2.5), 2.0 (1.3–3.0), 4.0 (1.5–10.3) and in patients using a statin versus other forms of medication for dyslipidaemia −1.7 (1.2–2.2), 1.7 (1.2–2.3), 4.4 (2.3–8.5).
Conclusions: Better medical insurance cover, care in a province-level hospital rather than county-level hospital, treatment by a non-cardiologist and use of a statin were associated with better compliance to lipid-lowering treatment.
Original language | English |
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Pages (from-to) | 229-237 |
Number of pages | 9 |
Journal | European Journal of Preventive Cardiology |
Volume | 20 |
Issue number | 2 |
Early online date | 9 Feb 2012 |
DOIs | |
Publication status | Published - Apr 2013 |
Keywords
- aged
- biological markers
- chi-square distribution
- China
- delivery of health care
- female
- health knowledge, attitudes, practice
- humans
- hydroxymethylglutaryl-CoA reductase inhibitors
- hyperlipidemias
- hypolipidemic agents
- insurance coverage
- insurance, health
- lipids
- logistic models
- male
- medication adherence
- middle aged
- odds ratio
- residence characteristics
- risk factors
- socioeconomic factors
- time factors
- treatment outcome
- compliance
- dyslipidaemia
- lipid-lowering therapy
- cardiovascular disease