Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008

N R V Jones, C M Fischbacher, B Guthrie, G Leese, R S Lindsay, J A McKnight, D Pearson, S Philip, N Sattar, S H Wild, Scottish Diabetes Research Network (SDRN) Epidemiology group

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Abstract

AIM: To describe characteristics associated with statin prescribing for the primary prevention of cardiovascular disease in people with newly diagnosed diabetes.

METHODS: Data from the Scottish Care Information-Diabetes Collaboration data set for 2006-2008 were used. This data set contains socio-demographic and prescribing data for over 99% of people with diagnosed diabetes in Scotland. Analyses were conducted on people aged over 40 years diagnosed with Type 1 or Type 2 diabetes between 2006 and 2008 with complete data and no previous history of cardiovascular or statin prescription. Logistic regression was used to calculate odds ratios for statin prescription in the 2 years following diagnosis of diabetes.

RESULTS: There were 7157 men and 5601 women who met the inclusion criteria, 68% of whom had a statin prescription recorded in the 2 years following diagnosis of diabetes. The proportions receiving statins were lower above 65 years of age in men and 75 years of age in women. People with Type 1 diabetes had lower odds of receiving statins than people with Type 2 diabetes [odds ratio (95% CI) 0.42 (0.29-0.61) for men and 0.48 (0.28-0.81) for women, after adjustment for age, BMI, smoking status, cholesterol level and deprivation]. Higher total cholesterol, BMI and being a current smoker were associated with greater odds of statin prescription.

CONCLUSION: Approximately one third of the study population had no record of statin prescription during the 2 years after diagnosis of diabetes. Cardiovascular disease risk reduction opportunities may be missed in some of these people.

Original languageEnglish
Pages (from-to)640-646
Number of pages7
JournalDiabetic Medicine
Volume31
Issue number6
Early online date24 Mar 2014
DOIs
Publication statusPublished - Jun 2014

Keywords

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Type 2
  • Diabetic Angiopathies
  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Hypoglycemic Agents
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Scotland
  • Sex Distribution

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    Jones, N. R. V., Fischbacher, C. M., Guthrie, B., Leese, G., Lindsay, R. S., McKnight, J. A., Pearson, D., Philip, S., Sattar, N., Wild, S. H., & Scottish Diabetes Research Network (SDRN) Epidemiology group (2014). Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008. Diabetic Medicine, 31(6), 640-646. https://doi.org/10.1111/dme.12409