Fast field-cycling magnetic resonance imaging

David J Lurie; Silvio Aime; Simona Baroni; Nuala Booth; Lionel Broche; Chang-Hoon Choi; Gareth R Davies; Saadiya  Ismail; Dara O Hogain; Kerrin J Pine

doi:10.1016/j.crhy.2010.06.012

Fast field-cycling magnetic resonance imaging

David J Lurie, Silvio Aime, Simona Baroni, Nuala Booth, Lionel Broche, Chang-Hoon Choi, Gareth R Davies, Saadiya Ismail, Dara O Hogain, Kerrin J Pine

Research output: Contribution to journal › Article

Abstract

Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques, and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth's field and pre-polarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.

Original language	English
Pages (from-to)	136-148
Number of pages	13
Journal	Comptes Rendus. Physique
Volume	11
Issue number	2
DOIs	https://doi.org/10.1016/j.crhy.2010.06.012
Publication status	Published - Mar 2010

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Lurie, D. J., Aime, S., Baroni, S., Booth, N., Broche, L., Choi, C-H., ... Pine, K. J. (2010). Fast field-cycling magnetic resonance imaging. Comptes Rendus. Physique, 11(2), 136-148. https://doi.org/10.1016/j.crhy.2010.06.012

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title = "Fast field-cycling magnetic resonance imaging",

abstract = "Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques, and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth's field and pre-polarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.",

author = "Lurie, {David J} and Silvio Aime and Simona Baroni and Nuala Booth and Lionel Broche and Chang-Hoon Choi and Davies, {Gareth R} and Saadiya Ismail and {O Hogain}, Dara and Pine, {Kerrin J}",

note = "Acknowledgements The authors acknowledge financial support for the FFC-MRI project from Research Councils UK and the Engineering and Physical Sciences Research Council, under the Basic Technology scheme (grant No. EP/E036775/1)",

year = "2010",

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doi = "10.1016/j.crhy.2010.06.012",

language = "English",

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AU - Lurie, David J

AU - Aime, Silvio

AU - Baroni, Simona

AU - Booth, Nuala

AU - Broche, Lionel

AU - Choi, Chang-Hoon

AU - Davies, Gareth R

AU - Ismail, Saadiya

AU - O Hogain, Dara

AU - Pine, Kerrin J

N1 - Acknowledgements The authors acknowledge financial support for the FFC-MRI project from Research Councils UK and the Engineering and Physical Sciences Research Council, under the Basic Technology scheme (grant No. EP/E036775/1)

PY - 2010/3

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N2 - Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques, and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth's field and pre-polarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.

AB - Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques, and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth's field and pre-polarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.

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