TY - JOUR
T1 - Fast field-cycling magnetic resonance imaging
AU - Lurie, David J
AU - Aime, Silvio
AU - Baroni, Simona
AU - Booth, Nuala
AU - Broche, Lionel
AU - Choi, Chang-Hoon
AU - Davies, Gareth R
AU - Ismail, Saadiya
AU - O Hogain, Dara
AU - Pine, Kerrin J
N1 - Acknowledgements The authors acknowledge financial support for the FFC-MRI project from Research Councils UK and the Engineering and Physical Sciences Research Council, under the Basic Technology scheme (grant No. EP/E036775/1)
PY - 2010/3
Y1 - 2010/3
N2 - Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques, and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth's field and pre-polarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.
AB - Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-developed methods. The combination of these techniques, namely fast field-cycling magnetic resonance imaging (FFC-MRI) is much less well-known. Nevertheless, FFC-MRI has a number of significant applications and advantages over conventional techniques, and is being pursued in a number of laboratories. This article reviews the progress in FFC-MRI over the last two decades, particularly in the areas of Earth's field and pre-polarised MRI, as well as free radical imaging using field-cycling Overhauser MRI. Different approaches to magnet design for FFC-MRI are also described. The paper then goes on to discuss recent techniques and applications of FFC-MRI, including protein measurement via quadrupolar cross-relaxation, contrast agent studies, localised relaxometry and FFC-MRI with magnetisation-transfer contrast.
UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-77956229493&doi=10.1016%2fj.crhy.2010.06.012&partnerID=40&md5=b3bf0071ac38a8e58b0082902d96fee8
U2 - 10.1016/j.crhy.2010.06.012
DO - 10.1016/j.crhy.2010.06.012
M3 - Article
VL - 11
SP - 136
EP - 148
JO - Comptes Rendus. Physique
JF - Comptes Rendus. Physique
SN - 1631-0705
IS - 2
ER -