Femoral geometry as a risk factor for osteoporotic hip fracture in men and women

Research output: Contribution to journalLiterature review

69 Citations (Scopus)

Abstract

Osteoporotic hip fracture is associated with high mortality and morbidity and often results in a loss of mobility and independence. Osteoporosis is diagnosed by measuring Bone Mineral Density (BMD), a measure of the amount of mineral in a bone. Although BMD continues to serve well it does not fully account for bone strength and only partially accounts for the risk of hip fracture. The shape and structure of the proximal femur also help to determine how forces act in the hip in a fall and their measurement can aid the prediction of hip fracture. This review examines the link between simple geometrical measures of the proximal femur and hip fracture, or bone strength. It will explore how they relate to each other and to anthropometric factors such as sex, height, weight and age. Limitations in these measures will be identified and new methods of analysis reviewed that encompass many different aspects of the shape of the femur. These new methods show great promise for improving the prediction of fracture risk in the future.
Original languageEnglish
Pages (from-to)1275-1286
Number of pages12
JournalMedical Engineering & Physics
Volume30
Issue number10
Early online date31 Oct 2008
DOIs
Publication statusPublished - Dec 2008

Fingerprint

Osteoporotic Fractures
Hip Fractures
Thigh
Bone
Femur
Geometry
Minerals
Bone Density
Pelvic Bones
Bone and Bones
Osteoporosis
Hip
Morbidity
Weights and Measures
Mortality

Keywords

  • Computer Simulation
  • Female
  • Femoral Fractures
  • Humans
  • Incidence
  • Male
  • Biological Models
  • Osteoporosis
  • Prevalence
  • Risk Assessment
  • Risk Factors
  • Sex Factors
  • Bone-Mineral Density
  • X-Ray absorptiometry
  • Finite-element models
  • Proximal femur geometry
  • Active shape models
  • Axis length
  • Postmenopausal women
  • Neck geometry
  • Trochanteric fractures
  • Hip
  • Fracture
  • Geometry
  • Shape
  • Imaging
  • Active Shape Modelling

Cite this

Femoral geometry as a risk factor for osteoporotic hip fracture in men and women. / Gregory, Jennifer S.; Aspden, Richard M.

In: Medical Engineering & Physics, Vol. 30, No. 10, 12.2008, p. 1275-1286.

Research output: Contribution to journalLiterature review

@article{451d3e4e6b4f4d17bba690771ca2f311,
title = "Femoral geometry as a risk factor for osteoporotic hip fracture in men and women",
abstract = "Osteoporotic hip fracture is associated with high mortality and morbidity and often results in a loss of mobility and independence. Osteoporosis is diagnosed by measuring Bone Mineral Density (BMD), a measure of the amount of mineral in a bone. Although BMD continues to serve well it does not fully account for bone strength and only partially accounts for the risk of hip fracture. The shape and structure of the proximal femur also help to determine how forces act in the hip in a fall and their measurement can aid the prediction of hip fracture. This review examines the link between simple geometrical measures of the proximal femur and hip fracture, or bone strength. It will explore how they relate to each other and to anthropometric factors such as sex, height, weight and age. Limitations in these measures will be identified and new methods of analysis reviewed that encompass many different aspects of the shape of the femur. These new methods show great promise for improving the prediction of fracture risk in the future.",
keywords = "Computer Simulation, Female, Femoral Fractures, Humans, Incidence, Male, Biological Models , Osteoporosis, Prevalence, Risk Assessment, Risk Factors, Sex Factors, Bone-Mineral Density, X-Ray absorptiometry, Finite-element models, Proximal femur geometry, Active shape models, Axis length, Postmenopausal women, Neck geometry, Trochanteric fractures, Hip, Fracture, Geometry, Shape, Imaging, Active Shape Modelling",
author = "Gregory, {Jennifer S.} and Aspden, {Richard M.}",
year = "2008",
month = "12",
doi = "10.1016/j.medengphy.2008.09.002",
language = "English",
volume = "30",
pages = "1275--1286",
journal = "Medical Engineering & Physics",
issn = "1350-4533",
publisher = "Elsevier BV",
number = "10",

}

TY - JOUR

T1 - Femoral geometry as a risk factor for osteoporotic hip fracture in men and women

AU - Gregory, Jennifer S.

AU - Aspden, Richard M.

PY - 2008/12

Y1 - 2008/12

N2 - Osteoporotic hip fracture is associated with high mortality and morbidity and often results in a loss of mobility and independence. Osteoporosis is diagnosed by measuring Bone Mineral Density (BMD), a measure of the amount of mineral in a bone. Although BMD continues to serve well it does not fully account for bone strength and only partially accounts for the risk of hip fracture. The shape and structure of the proximal femur also help to determine how forces act in the hip in a fall and their measurement can aid the prediction of hip fracture. This review examines the link between simple geometrical measures of the proximal femur and hip fracture, or bone strength. It will explore how they relate to each other and to anthropometric factors such as sex, height, weight and age. Limitations in these measures will be identified and new methods of analysis reviewed that encompass many different aspects of the shape of the femur. These new methods show great promise for improving the prediction of fracture risk in the future.

AB - Osteoporotic hip fracture is associated with high mortality and morbidity and often results in a loss of mobility and independence. Osteoporosis is diagnosed by measuring Bone Mineral Density (BMD), a measure of the amount of mineral in a bone. Although BMD continues to serve well it does not fully account for bone strength and only partially accounts for the risk of hip fracture. The shape and structure of the proximal femur also help to determine how forces act in the hip in a fall and their measurement can aid the prediction of hip fracture. This review examines the link between simple geometrical measures of the proximal femur and hip fracture, or bone strength. It will explore how they relate to each other and to anthropometric factors such as sex, height, weight and age. Limitations in these measures will be identified and new methods of analysis reviewed that encompass many different aspects of the shape of the femur. These new methods show great promise for improving the prediction of fracture risk in the future.

KW - Computer Simulation

KW - Female

KW - Femoral Fractures

KW - Humans

KW - Incidence

KW - Male

KW - Biological Models

KW - Osteoporosis

KW - Prevalence

KW - Risk Assessment

KW - Risk Factors

KW - Sex Factors

KW - Bone-Mineral Density

KW - X-Ray absorptiometry

KW - Finite-element models

KW - Proximal femur geometry

KW - Active shape models

KW - Axis length

KW - Postmenopausal women

KW - Neck geometry

KW - Trochanteric fractures

KW - Hip

KW - Fracture

KW - Geometry

KW - Shape

KW - Imaging

KW - Active Shape Modelling

U2 - 10.1016/j.medengphy.2008.09.002

DO - 10.1016/j.medengphy.2008.09.002

M3 - Literature review

C2 - 18976949

VL - 30

SP - 1275

EP - 1286

JO - Medical Engineering & Physics

JF - Medical Engineering & Physics

SN - 1350-4533

IS - 10

ER -