Abstract
A composition comprising a translocation sequence derived from a fish pathogen and a heterologous payload coupled to the translocation sequence is provided. The composition is able to translocate across the plasma membrane of a eukaryotic cell, for example a fish cell, and thus stimulate an immune response. Accordingly, nucleic acids, vectors, host cells, compositions and vaccines based thereon are also provided.
Original language | English |
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Patent number | WO2014191759 |
IPC | A61K38/16; C07K14/37; C12N15/62 |
Priority date | 30/05/13 |
Publication status | Published - 4 Dec 2014 |