Flawed Comparative Groups Lead to Flawed Conclusions: Response

Christopher C. Winchester; Tatiana Macfarlane; Mike Thomas; David Price

doi:10.1378/chest.09-1449

Flawed Comparative Groups Lead to Flawed Conclusions: Response

Christopher C. Winchester^* (Corresponding Author), Tatiana Macfarlane, Mike Thomas, David Price

^*Corresponding author for this work

Research output: Contribution to journal › Letter › peer-review

Abstract

Our observational study1 of patients with lower respiratory tract infection (LRTI) presenting in the primary care setting showed a decrease in hospital admissions and mortality among patients who were prescribed an antibiotic on the day of consultation compared with those who did not receive such treatment. This association remained statistically significant after other potential factors influencing the outcomes of LRTI were taken into account in a multivariate model. These factors included comorbidity and its proxies, frequent health-care utilization and prior antibiotic use.

Original language	English
Pages (from-to)	1185-1186
Number of pages	2
Journal	Chest
Volume	136
Issue number	4
DOIs	https://doi.org/10.1378/chest.09-1449
Publication status	Published - Oct 2009

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http://www.sciencedirect.com/science/article/pii/S0012369209606334

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title = "Flawed Comparative Groups Lead to Flawed Conclusions: Response",

abstract = "Our observational study1 of patients with lower respiratory tract infection (LRTI) presenting in the primary care setting showed a decrease in hospital admissions and mortality among patients who were prescribed an antibiotic on the day of consultation compared with those who did not receive such treatment. This association remained statistically significant after other potential factors influencing the outcomes of LRTI were taken into account in a multivariate model. These factors included comorbidity and its proxies, frequent health-care utilization and prior antibiotic use.",

author = "Winchester, {Christopher C.} and Tatiana Macfarlane and Mike Thomas and David Price",

year = "2009",

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doi = "10.1378/chest.09-1449",

language = "English",

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TY - JOUR

T1 - Flawed Comparative Groups Lead to Flawed Conclusions

T2 - Response

AU - Winchester, Christopher C.

AU - Macfarlane, Tatiana

AU - Thomas, Mike

AU - Price, David

PY - 2009/10

Y1 - 2009/10

N2 - Our observational study1 of patients with lower respiratory tract infection (LRTI) presenting in the primary care setting showed a decrease in hospital admissions and mortality among patients who were prescribed an antibiotic on the day of consultation compared with those who did not receive such treatment. This association remained statistically significant after other potential factors influencing the outcomes of LRTI were taken into account in a multivariate model. These factors included comorbidity and its proxies, frequent health-care utilization and prior antibiotic use.

AB - Our observational study1 of patients with lower respiratory tract infection (LRTI) presenting in the primary care setting showed a decrease in hospital admissions and mortality among patients who were prescribed an antibiotic on the day of consultation compared with those who did not receive such treatment. This association remained statistically significant after other potential factors influencing the outcomes of LRTI were taken into account in a multivariate model. These factors included comorbidity and its proxies, frequent health-care utilization and prior antibiotic use.

U2 - 10.1378/chest.09-1449

DO - 10.1378/chest.09-1449

M3 - Letter

SN - 0012-3692

VL - 136

SP - 1185

EP - 1186

JO - Chest

JF - Chest

IS - 4

ER -

Flawed Comparative Groups Lead to Flawed Conclusions: Response

Abstract

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