Fluorinated Inhibitors of Matrix Metalloproteinases

Roberta Sinisi, Monika Jagodzinska, Gabriele Candiani, Florent Huguenot, Monica Sani, Alessandro Volonterio, Raffaella Maffezzoni, Matteo Zanda

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationFluorine in Medicinal Chemistry and Chemical Biology
EditorsIwao Ojima
Place of PublicationOxford, United Kingdom
PublisherWiley-Blackwell
Pages99-115
Number of pages17
ISBN (Electronic)978-1444312096
ISBN (Print)1405167203 , 978-1405167208
DOIs
Publication statusPublished - 9 Jun 2009

Keywords

  • fluorinated inhibitors of matrix metalloproteinases
  • matrix metalloproteinases
  • family of highly homologous Zn(II)-endopeptidases
  • degradation of extracellular matrix and connective tissue remodeling
  • a-CF3-malic hydroxamate inhibitors
  • Jacobsen's potent peptidomimetic hydroxamate inhibitors
  • a -trifluoromethyl-a-amino-ß-sulfone hydroxamate inhibitors
  • nanomolar CF3-barbituric acid inhibitor selective for MMP-9

Cite this

Sinisi, R., Jagodzinska, M., Candiani, G., Huguenot, F., Sani, M., Volonterio, A., ... Zanda, M. (2009). Fluorinated Inhibitors of Matrix Metalloproteinases. In I. Ojima (Ed.), Fluorine in Medicinal Chemistry and Chemical Biology (pp. 99-115). Oxford, United Kingdom: Wiley-Blackwell . https://doi.org/10.1002/9781444312096.ch4

Fluorinated Inhibitors of Matrix Metalloproteinases. / Sinisi, Roberta; Jagodzinska, Monika; Candiani, Gabriele; Huguenot, Florent; Sani, Monica; Volonterio, Alessandro; Maffezzoni, Raffaella; Zanda, Matteo.

Fluorine in Medicinal Chemistry and Chemical Biology. ed. / Iwao Ojima. Oxford, United Kingdom : Wiley-Blackwell , 2009. p. 99-115.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sinisi, R, Jagodzinska, M, Candiani, G, Huguenot, F, Sani, M, Volonterio, A, Maffezzoni, R & Zanda, M 2009, Fluorinated Inhibitors of Matrix Metalloproteinases. in I Ojima (ed.), Fluorine in Medicinal Chemistry and Chemical Biology. Wiley-Blackwell , Oxford, United Kingdom, pp. 99-115. https://doi.org/10.1002/9781444312096.ch4
Sinisi R, Jagodzinska M, Candiani G, Huguenot F, Sani M, Volonterio A et al. Fluorinated Inhibitors of Matrix Metalloproteinases. In Ojima I, editor, Fluorine in Medicinal Chemistry and Chemical Biology. Oxford, United Kingdom: Wiley-Blackwell . 2009. p. 99-115 https://doi.org/10.1002/9781444312096.ch4
Sinisi, Roberta ; Jagodzinska, Monika ; Candiani, Gabriele ; Huguenot, Florent ; Sani, Monica ; Volonterio, Alessandro ; Maffezzoni, Raffaella ; Zanda, Matteo. / Fluorinated Inhibitors of Matrix Metalloproteinases. Fluorine in Medicinal Chemistry and Chemical Biology. editor / Iwao Ojima. Oxford, United Kingdom : Wiley-Blackwell , 2009. pp. 99-115
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