Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Sheng Huang, Long Ma, Ming Him Tong, Yi Yu (Corresponding Author), David O'Hagan, Hai Deng (Corresponding Author)

Research output: Contribution to journalArticle

29 Citations (Scopus)


Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.

Original languageEnglish
Pages (from-to)4828-4831
Number of pages4
JournalOrganic & Biomolecular Chemistry
Issue number12
Early online date30 May 2014
Publication statusPublished - 21 Jul 2014


Cite this