Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Sheng Huang; Long Ma; Ming Him Tong; Yi Yu; David O'Hagan; Hai Deng

doi:10.1039/c4ob00970c

Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Sheng Huang, Long Ma, Ming Him Tong, Yi Yu^* (Corresponding Author), David O'Hagan, Hai Deng^* (Corresponding Author)

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.

Original language	English
Pages (from-to)	4828-4831
Number of pages	4
Journal	Organic & Biomolecular Chemistry
Volume	27
Issue number	12
Early online date	30 May 2014
DOIs	https://doi.org/10.1039/c4ob00970c
Publication status	Published - 21 Jul 2014

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title = "Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674",

abstract = "Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.",

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AU - Huang, Sheng

AU - Ma, Long

AU - Tong, Ming Him

AU - Yu, Yi

AU - O'Hagan, David

AU - Deng, Hai

PY - 2014/7/21

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AB - Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluorometabolite producing microorganism identified from the marine environment.

U2 - 10.1039/c4ob00970c

DO - 10.1039/c4ob00970c

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SN - 1477-0520

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ER -

Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Abstract

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