Abstract
Original language | English |
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Pages (from-to) | 150-158 |
Number of pages | 9 |
Journal | Computerized Medical Imaging and Graphics |
Volume | 32 |
Issue number | 2 |
Early online date | 18 Dec 2007 |
DOIs | |
Publication status | Published - 31 Mar 2008 |
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Keywords
- Fractal dimension
- Brain imaging
- Schizophrenia
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Fractal dimension analysis of MR images reveals grey matter structure irregularities in schizophrenia. / Sandu-Giuraniuc, Anca-Larisa (Corresponding Author); Rasmussen Jr., Inge-Andre; Lundervold, Arvid ; Kreuder, Frank; Neckelmann, Gesche; Hugdahl, Kenneth; Specht, Karsten.
In: Computerized Medical Imaging and Graphics, Vol. 32, No. 2, 31.03.2008, p. 150-158.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Fractal dimension analysis of MR images reveals grey matter structure irregularities in schizophrenia.
AU - Sandu-Giuraniuc, Anca-Larisa
AU - Rasmussen Jr., Inge-Andre
AU - Lundervold, Arvid
AU - Kreuder, Frank
AU - Neckelmann, Gesche
AU - Hugdahl, Kenneth
AU - Specht, Karsten
N1 - The present research was financially supported by a grant to Kenneth Hugdahl from the Alfried Krupp von Bohlen und Halbach Stiftung, Germany. The software and the data sets can be made available to other researchers after inquiry to the principal investigator, Kenneth Hugdahl.
PY - 2008/3/31
Y1 - 2008/3/31
N2 - The fractal dimension (FD) was used to reveal brain structure irregularities in patients with schizophrenia. FD provides a unique way of quantifying the shape complexity of cortical folding of the human brain. MR images were obtained from seven patients with schizophrenia that were compared with six healthy control subjects. The MR images were first segmented, and the FD was calculated for the grey/white matter boundary for the whole brain and the hemispheres separately, using the box-counting and Minkowski-Bouligand methods. The results showed that the patients had larger FD values than the controls, for the whole brain volume and right hemisphere.
AB - The fractal dimension (FD) was used to reveal brain structure irregularities in patients with schizophrenia. FD provides a unique way of quantifying the shape complexity of cortical folding of the human brain. MR images were obtained from seven patients with schizophrenia that were compared with six healthy control subjects. The MR images were first segmented, and the FD was calculated for the grey/white matter boundary for the whole brain and the hemispheres separately, using the box-counting and Minkowski-Bouligand methods. The results showed that the patients had larger FD values than the controls, for the whole brain volume and right hemisphere.
KW - Fractal dimension
KW - Brain imaging
KW - Schizophrenia
U2 - 10.1016/j.compmedimag.2007.10.005
DO - 10.1016/j.compmedimag.2007.10.005
M3 - Article
VL - 32
SP - 150
EP - 158
JO - Computerized Medical Imaging and Graphics
JF - Computerized Medical Imaging and Graphics
SN - 0895-6111
IS - 2
ER -