From commensal to pathogen: Candida albicans

Amy Whittington, Neil A.R. Gow, Bernhard Hube

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Citations (Scopus)

Abstract

The attributes that allow Candida albicans to be a successful human commensal overlap with its ability to cause opportunistic disease. The ways in which C. albicans successfully transitions from a commensal to a pathogen involve many aspects of its growth and interaction with the host, including the host recognition of and response to the various cell types that characterise this fungal species. We discuss the factors that are important for commensal growth, stress responses, the role of the cell wall in immune recognition, attachment to and interactions with epithelial cells, and interactions with immune cells as key aspects of the commensal-pathogenic life style of this fungus.

Original languageEnglish
Title of host publicationHuman Fungal Pathogens
PublisherSpringer Berlin / Heidelberg
Pages3-18
Number of pages16
Volume12
Edition2
ISBN (Electronic)9783642394324
ISBN (Print)9783642394317
DOIs
Publication statusPublished - 1 Jan 2014

Publication series

NameThe Mycota

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