From Molecules to organisms: towards multiscale integrated models of biological systems

Christophe Lavelle, Hugues Berry, Guillaume Beslon, Francesco Giulio Ginelli, Jean-Louis Giavitto, Zoi Kapoula, André Le Bivic, Nadine Peyrieras, Ovidiu Radulescu, Adrien Six, Veronique Thomas-Vaslin, Paul Bourgine

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Abstract

A consensus has recently emerged that further progress in understanding human physiopathology will demand integrative views of biological systems. In this context, complex systems and related interdisciplinary approaches of biology are expected to help. The aim of this collective paper is basically to provide a starting point for further discussions and interactions within the community of complex systems biologists. After briefly introducing some general concepts, we present four major challenges that should be tackled in the next years. These represent future directions that we isolated as priority concerns for modern biology. Suggestions of how to reach these destinations are provided, with the hope that they will soon lead to concrete advances towards fully consistent multiscale models of biological systems and a better understanding of physiopathology.
Original languageEnglish
Pages (from-to)13-22
Number of pages10
JournalTheoretical Biology Insights
Volume1
Issue number1
Publication statusPublished - 29 Sep 2008

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Lavelle, C., Berry, H., Beslon, G., Ginelli, F. G., Giavitto, J-L., Kapoula, Z., ... Bourgine, P. (2008). From Molecules to organisms: towards multiscale integrated models of biological systems. Theoretical Biology Insights, 1(1), 13-22.

From Molecules to organisms : towards multiscale integrated models of biological systems. / Lavelle, Christophe; Berry, Hugues; Beslon, Guillaume; Ginelli, Francesco Giulio; Giavitto, Jean-Louis; Kapoula, Zoi; Le Bivic, André; Peyrieras, Nadine; Radulescu, Ovidiu; Six, Adrien; Thomas-Vaslin, Veronique; Bourgine, Paul.

In: Theoretical Biology Insights, Vol. 1, No. 1, 29.09.2008, p. 13-22.

Research output: Contribution to journalArticle

Lavelle, C, Berry, H, Beslon, G, Ginelli, FG, Giavitto, J-L, Kapoula, Z, Le Bivic, A, Peyrieras, N, Radulescu, O, Six, A, Thomas-Vaslin, V & Bourgine, P 2008, 'From Molecules to organisms: towards multiscale integrated models of biological systems', Theoretical Biology Insights, vol. 1, no. 1, pp. 13-22.
Lavelle C, Berry H, Beslon G, Ginelli FG, Giavitto J-L, Kapoula Z et al. From Molecules to organisms: towards multiscale integrated models of biological systems. Theoretical Biology Insights. 2008 Sep 29;1(1):13-22.
Lavelle, Christophe ; Berry, Hugues ; Beslon, Guillaume ; Ginelli, Francesco Giulio ; Giavitto, Jean-Louis ; Kapoula, Zoi ; Le Bivic, André ; Peyrieras, Nadine ; Radulescu, Ovidiu ; Six, Adrien ; Thomas-Vaslin, Veronique ; Bourgine, Paul. / From Molecules to organisms : towards multiscale integrated models of biological systems. In: Theoretical Biology Insights. 2008 ; Vol. 1, No. 1. pp. 13-22.
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