From Molecules to organisms: towards multiscale integrated models of biological systems

Christophe Lavelle; Hugues Berry; Guillaume Beslon; Francesco Giulio Ginelli; Jean-Louis Giavitto; Zoi Kapoula; André Le Bivic; Nadine Peyrieras; Ovidiu Radulescu; Adrien Six; Veronique Thomas-Vaslin; Paul Bourgine

From Molecules to organisms: towards multiscale integrated models of biological systems

Christophe Lavelle, Hugues Berry, Guillaume Beslon, Francesco Giulio Ginelli, Jean-Louis Giavitto, Zoi Kapoula, André Le Bivic, Nadine Peyrieras, Ovidiu Radulescu, Adrien Six, Veronique Thomas-Vaslin, Paul Bourgine

Physics

Research output: Contribution to journal › Article › peer-review

Abstract

A consensus has recently emerged that further progress in understanding human physiopathology will demand integrative views of biological systems. In this context, complex systems and related interdisciplinary approaches of biology are expected to help. The aim of this collective paper is basically to provide a starting point for further discussions and interactions within the community of complex systems biologists. After briefly introducing some general concepts, we present four major challenges that should be tackled in the next years. These represent future directions that we isolated as priority concerns for modern biology. Suggestions of how to reach these destinations are provided, with the hope that they will soon lead to concrete advances towards fully consistent multiscale models of biological systems and a better understanding of physiopathology.

Original language	English
Pages (from-to)	13-22
Number of pages	10
Journal	Theoretical Biology Insights
Volume	1
Issue number	1
Publication status	Published - 29 Sep 2008

Cite this

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title = "From Molecules to organisms: towards multiscale integrated models of biological systems",

abstract = "A consensus has recently emerged that further progress in understanding human physiopathology will demand integrative views of biological systems. In this context, complex systems and related interdisciplinary approaches of biology are expected to help. The aim of this collective paper is basically to provide a starting point for further discussions and interactions within the community of complex systems biologists. After briefly introducing some general concepts, we present four major challenges that should be tackled in the next years. These represent future directions that we isolated as priority concerns for modern biology. Suggestions of how to reach these destinations are provided, with the hope that they will soon lead to concrete advances towards fully consistent multiscale models of biological systems and a better understanding of physiopathology.",

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T2 - towards multiscale integrated models of biological systems

AU - Lavelle, Christophe

AU - Berry, Hugues

AU - Beslon, Guillaume

AU - Ginelli, Francesco Giulio

AU - Giavitto, Jean-Louis

AU - Kapoula, Zoi

AU - Le Bivic, André

AU - Peyrieras, Nadine

AU - Radulescu, Ovidiu

AU - Six, Adrien

AU - Thomas-Vaslin, Veronique

AU - Bourgine, Paul

PY - 2008/9/29

Y1 - 2008/9/29

N2 - A consensus has recently emerged that further progress in understanding human physiopathology will demand integrative views of biological systems. In this context, complex systems and related interdisciplinary approaches of biology are expected to help. The aim of this collective paper is basically to provide a starting point for further discussions and interactions within the community of complex systems biologists. After briefly introducing some general concepts, we present four major challenges that should be tackled in the next years. These represent future directions that we isolated as priority concerns for modern biology. Suggestions of how to reach these destinations are provided, with the hope that they will soon lead to concrete advances towards fully consistent multiscale models of biological systems and a better understanding of physiopathology.

AB - A consensus has recently emerged that further progress in understanding human physiopathology will demand integrative views of biological systems. In this context, complex systems and related interdisciplinary approaches of biology are expected to help. The aim of this collective paper is basically to provide a starting point for further discussions and interactions within the community of complex systems biologists. After briefly introducing some general concepts, we present four major challenges that should be tackled in the next years. These represent future directions that we isolated as priority concerns for modern biology. Suggestions of how to reach these destinations are provided, with the hope that they will soon lead to concrete advances towards fully consistent multiscale models of biological systems and a better understanding of physiopathology.

M3 - Article

VL - 1

SP - 13

EP - 22

JO - Theoretical Biology Insights

JF - Theoretical Biology Insights

IS - 1

ER -

From Molecules to organisms: towards multiscale integrated models of biological systems

Abstract

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