Fungal Recognition and Host Defense Mechanisms

I. M. Dambuza, S. M Levitz, M. G. Netea, G. D. Brown

Research output: Contribution to journalArticle

7 Citations (Scopus)
6 Downloads (Pure)

Abstract

Fungi have emerged as premier opportunistic microbes of the 21st century, having a considerable impact on human morbidity and mortality. The huge increase in incidence of these diseases is largely due to the HIV pandemic and use of immunosuppressive therapies, underscoring the importance of the immune system in defense against fungi. This article will address how the mammalian immune system recognizes and mounts a defense against medically relevant fungal species.
Original languageEnglish
Pages (from-to)1-16
Number of pages16
JournalMicrobiology spectrum
Volume5
Issue number4
DOIs
Publication statusPublished - 28 Jul 2017

Fingerprint

defense mechanism
immune system
Immune System
Fungi
fungus
twenty first century
Pandemics
morbidity
Immunosuppressive Agents
human immunodeficiency virus
HIV
Morbidity
mortality
Mortality
Incidence
defence
Therapeutics
therapy

Cite this

Dambuza, I. M., Levitz, S. M., Netea, M. G., & Brown, G. D. (2017). Fungal Recognition and Host Defense Mechanisms. Microbiology spectrum, 5(4), 1-16. https://doi.org/10.1128/microbiolspec.FUNK-0050-2016

Fungal Recognition and Host Defense Mechanisms. / Dambuza, I. M.; Levitz, S. M; Netea, M. G.; Brown, G. D.

In: Microbiology spectrum, Vol. 5, No. 4, 28.07.2017, p. 1-16.

Research output: Contribution to journalArticle

Dambuza, IM, Levitz, SM, Netea, MG & Brown, GD 2017, 'Fungal Recognition and Host Defense Mechanisms', Microbiology spectrum, vol. 5, no. 4, pp. 1-16. https://doi.org/10.1128/microbiolspec.FUNK-0050-2016
Dambuza, I. M. ; Levitz, S. M ; Netea, M. G. ; Brown, G. D. / Fungal Recognition and Host Defense Mechanisms. In: Microbiology spectrum. 2017 ; Vol. 5, No. 4. pp. 1-16.
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