‘Genetic Coding’ Reconsidered

An Analysis of Actual Usage

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Abstract

This article reconsiders the theoretical role of the genetic code. By drawing on published and unpublished sources from the 1950s, I analyse how the code metaphor was actually employed by the scientists who first promoted its use. The analysis shows that the term ‘code’ picked out mechanism sketches, consisting of more or less detailed descriptions of ordinary molecular components, processes, and structural properties of the mechanism of protein synthesis. The sketches provided how-possibly explanations for the ordering of amino acids by nucleic acids (the ‘coding problem’). I argue that employing the code metaphor was justified in virtue of its descriptive-denotational and explanatory roles, and because it highlighted a similarity with conventional codes that was particularly salient at the time.
Original languageEnglish
Pages (from-to)707-730
Number of pages24
JournalBritish Journal for the Philosophy of Science
Volume67
Issue number3
Early online date15 Mar 2015
DOIs
Publication statusPublished - Sep 2016

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Descriptive
Genetic Code
Amino Acids
1950s
Structural Properties
Conventional
Salient
Protein Synthesis

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‘Genetic Coding’ Reconsidered : An Analysis of Actual Usage. / Stegmann, Ulrich E.

In: British Journal for the Philosophy of Science, Vol. 67, No. 3, 09.2016, p. 707-730.

Research output: Contribution to journalArticle

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