Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

Boni A Afouda, Adam T Lynch, Eduardo De Paiva Alves, Stefan Hoppler (Corresponding Author)

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Abstract

The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (B.A. Afouda, A.T. Lynch, E. de Paiva Alves, S. Hoppler, 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.
Original languageEnglish
Pages (from-to)559-563
Number of pages5
JournalData in brief
Volume17
Early online date17 Jan 2018
DOIs
Publication statusPublished - Apr 2018

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Xenopus laevis
GATA Transcription Factors
Genome
GATA5 Transcription Factor
GATA6 Transcription Factor
Myocardium
GATA4 Transcription Factor
Genes
Gene Ontology
Gene Regulatory Networks
Research

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Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis. / Afouda, Boni A; Lynch, Adam T; De Paiva Alves, Eduardo; Hoppler, Stefan (Corresponding Author).

In: Data in brief, Vol. 17, 04.2018, p. 559-563.

Research output: Contribution to journalArticle

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