Growth hormone in the critically ill

Nigel R. Webster*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Negative nitrogen balance is common in critically ill patients with prolonged intensive care unit stay. Growth hormone supplementation associated with adequate nutritional support in other patient groups resulted in preserved nitrogen balance. Despite the initial promising results of small trials, the large multicenter randomized controlled trial by Takala and colleagues showed that supranormal growth hormone supplementation in critically ill patients increased mortality and morbidity. Therefore, the use of growth hormone in intensive care unit in adult patients who are not known to be severely deficient is still considered inappropriate.

Original languageEnglish
Title of host publicationReducing Mortality in Critically Ill Patients
EditorsGiovanni Landoni, Marta Mucchetti, Alberto Zangrillo, Rinaldo Bellomo
PublisherSpringer International Publishing
Pages79-82
Number of pages4
ISBN (Print)9783319175157, 9783319175140
DOIs
Publication statusPublished - 2015

Fingerprint

Critical Illness
Growth Hormone
Intensive Care Units
Nitrogen
Nutritional Support
Multicenter Studies
Randomized Controlled Trials
Morbidity
Mortality

Keywords

  • Critically ill
  • Growth hormone
  • Mortality

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Webster, N. R. (2015). Growth hormone in the critically ill. In G. Landoni, M. Mucchetti, A. Zangrillo, & R. Bellomo (Eds.), Reducing Mortality in Critically Ill Patients (pp. 79-82). Springer International Publishing. https://doi.org/10.1007/978-3-319-17515-7_10

Growth hormone in the critically ill. / Webster, Nigel R.

Reducing Mortality in Critically Ill Patients. ed. / Giovanni Landoni; Marta Mucchetti; Alberto Zangrillo; Rinaldo Bellomo. Springer International Publishing, 2015. p. 79-82.

Research output: Chapter in Book/Report/Conference proceedingChapter

Webster, NR 2015, Growth hormone in the critically ill. in G Landoni, M Mucchetti, A Zangrillo & R Bellomo (eds), Reducing Mortality in Critically Ill Patients. Springer International Publishing, pp. 79-82. https://doi.org/10.1007/978-3-319-17515-7_10
Webster NR. Growth hormone in the critically ill. In Landoni G, Mucchetti M, Zangrillo A, Bellomo R, editors, Reducing Mortality in Critically Ill Patients. Springer International Publishing. 2015. p. 79-82 https://doi.org/10.1007/978-3-319-17515-7_10
Webster, Nigel R. / Growth hormone in the critically ill. Reducing Mortality in Critically Ill Patients. editor / Giovanni Landoni ; Marta Mucchetti ; Alberto Zangrillo ; Rinaldo Bellomo. Springer International Publishing, 2015. pp. 79-82
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