Gut microbiota

Microbiota organisation-a key to understanding CRC development

Georgina L Hold, Wendy S Garrett

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.
Original languageEnglish
Pages (from-to)128-129
Number of pages2
JournalNature Reviews Gastroenterology & Hepatology
Volume12
Issue number3
Early online date17 Feb 2015
DOIs
Publication statusPublished - Mar 2015

Fingerprint

Microbiota
Colorectal Neoplasms
Biofilms
Carcinogenesis
Gastrointestinal Microbiome
Neoplasms

Keywords

  • colorectal cancer
  • microbiome
  • microbiota

Cite this

Gut microbiota : Microbiota organisation-a key to understanding CRC development. / Hold, Georgina L; Garrett, Wendy S.

In: Nature Reviews Gastroenterology & Hepatology, Vol. 12, No. 3, 03.2015, p. 128-129.

Research output: Contribution to journalArticle

Hold, Georgina L ; Garrett, Wendy S. / Gut microbiota : Microbiota organisation-a key to understanding CRC development. In: Nature Reviews Gastroenterology & Hepatology. 2015 ; Vol. 12, No. 3. pp. 128-129.
@article{4c0d2f764d1e4205819c4c1db3071433,
title = "Gut microbiota: Microbiota organisation-a key to understanding CRC development",
abstract = "The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.",
keywords = "colorectal cancer, microbiome, microbiota",
author = "Hold, {Georgina L} and Garrett, {Wendy S}",
year = "2015",
month = "3",
doi = "10.1038/nrgastro.2015.25",
language = "English",
volume = "12",
pages = "128--129",
journal = "Nature Reviews Gastroenterology & Hepatology",
issn = "1759-5045",
publisher = "Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.",
number = "3",

}

TY - JOUR

T1 - Gut microbiota

T2 - Microbiota organisation-a key to understanding CRC development

AU - Hold, Georgina L

AU - Garrett, Wendy S

PY - 2015/3

Y1 - 2015/3

N2 - The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.

AB - The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.

KW - colorectal cancer

KW - microbiome

KW - microbiota

U2 - 10.1038/nrgastro.2015.25

DO - 10.1038/nrgastro.2015.25

M3 - Article

VL - 12

SP - 128

EP - 129

JO - Nature Reviews Gastroenterology & Hepatology

JF - Nature Reviews Gastroenterology & Hepatology

SN - 1759-5045

IS - 3

ER -