The gut microbiota has an important role in colorectal cancer (CRC). Dejea and colleagues have demonstrated that particular bacterial biofilms are associated with proximal CRC, correlating with changes in tissue biology associated with oncogenesis. These findings provide a fresh perspective on the microbiota in cancer: microbial organization might provide critical insight into understanding CRC development.
- colorectal cancer
Hold, G. L., & Garrett, W. S. (2015). Gut microbiota: Microbiota organisation-a key to understanding CRC development. Nature Reviews Gastroenterology & Hepatology, 12(3), 128-129. https://doi.org/10.1038/nrgastro.2015.25