TY - JOUR
T1 - Health, educational and employment outcomes among children treated for a skin disorder
T2 - Scotland-wide retrospective record linkage cohort study of 766,244 children
AU - Fleming, Michael
AU - McLay, James S.
AU - Clark, David
AU - King, Albert
AU - Mackay, Daniel F.
AU - Pell, Jill P.
N1 - Acknowledgments
The authors would like to acknowledge the support of the electronic Data Research and Innovation Services (eDRIS) within Public Health Scotland for their involvement in obtaining approvals, provisioning, and linking data and the use of the secure analytical platform within the National Safe Haven.
Funding: The study was sponsored by Health Data Research UK (www.hdruk.ac.uk) (grant reference number MR/S003800/1 awarded to Dr Michael Fleming) which is a joint investment led by the Medical Research Council, together with the National Institute for Health Research (England),
the Chief Scientist Office (Scotland), Health and Care Research Wales, Health and Social Care Research and Development Division (Public Health Agency, Northern Ireland), the Engineering and Physical Sciences Research Council, the Economic
and Social Research Council, the British Heart Foundation and Wellcome Trust. The sponsor and funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review or approval of the manuscript, or decision to submit the manuscript for publication.
PY - 2020/12/11
Y1 - 2020/12/11
N2 - BackgroundTo compare health, educational and employment outcomes of schoolchildren receiving medication for a skin disorder with peers.MethodsThis retrospective population cohort study linked eight Scotland-wide databases, covering dispensed prescriptions, hospital admissions, maternity records, death certificates, annual pupil census, school examinations, school absences/exclusions and unemployment to investigate educational (absence, exclusion, special educational need, academic attainment), employment, and health (admissions and mortality) outcomes of 766,244 children attending local authority run primary, secondary and special schools in Scotland between 2009 and 2013.ResultsAfter adjusting for sociodemographic and maternity confounders the 130,087 (17.0%) children treated for a skin disorder had increased hospitalisation, particularly within one year of commencing treatment (IRR 1.38, 95% CI 1.35-1.41, pConclusionsDespite increased hospitalisation, school absenteeism, and special educational need, children treated for a skin disorder did not have poorer exam attainment or employment outcomes. Whilst findings relating to educational and employment outcomes are reassuring, the association with increased risk of mortality is alarming and merits further investigation.
AB - BackgroundTo compare health, educational and employment outcomes of schoolchildren receiving medication for a skin disorder with peers.MethodsThis retrospective population cohort study linked eight Scotland-wide databases, covering dispensed prescriptions, hospital admissions, maternity records, death certificates, annual pupil census, school examinations, school absences/exclusions and unemployment to investigate educational (absence, exclusion, special educational need, academic attainment), employment, and health (admissions and mortality) outcomes of 766,244 children attending local authority run primary, secondary and special schools in Scotland between 2009 and 2013.ResultsAfter adjusting for sociodemographic and maternity confounders the 130,087 (17.0%) children treated for a skin disorder had increased hospitalisation, particularly within one year of commencing treatment (IRR 1.38, 95% CI 1.35-1.41, pConclusionsDespite increased hospitalisation, school absenteeism, and special educational need, children treated for a skin disorder did not have poorer exam attainment or employment outcomes. Whilst findings relating to educational and employment outcomes are reassuring, the association with increased risk of mortality is alarming and merits further investigation.
KW - ATOPIC-DERMATITIS
KW - UNITED-STATES
KW - PSORIASIS
KW - BURDEN
KW - ECZEMA
KW - COMORBIDITY
KW - ASSOCIATION
KW - PREVALENCE
KW - MORTALITY
KW - RISK
U2 - 10.1371/journal.pone.0243383
DO - 10.1371/journal.pone.0243383
M3 - Article
VL - 15
JO - PloS ONE
JF - PloS ONE
SN - 1932-6203
IS - 12
M1 - 0243383
ER -