Abstract
The cytotoxic activity of the tropane alkaloids, hederacine A (1) and hederacine B (2), previously isolated from the methanol extract of the aerial parts of Glechoma hederaceae, was assessed by the MTT cytotoxicity assay using colon cancer cell line (CaCo-2). The IC50 values for 1 and 2 were found to be 86.6 and 301.0 mu M, respectively.
Original language | English |
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Pages (from-to) | 33-35 |
Number of pages | 2 |
Journal | Natural Product Communications |
Volume | 1 |
Issue number | 1 |
Publication status | Published - 2006 |
Keywords
- glechoma hederaceae
- Lamiaceae
- hederacine A
- hederacine 13
- tropane alkaloid
- colon cancer
- MTT
- STRUCTURE ELUCIDATION
- MULTIDRUG-RESISTANCE