How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence

Patrice Forget* (Corresponding Author), Jose A. Aguirre, Ivanka Bencic, Alain Borgeat, Allessandro Cama, Claire Condron, Christina Eintrei, Pilar Eroles, Anil Gupta, Tim G. Hales, Daniela Ionescu, Mark Johnson, Pawel Kabata, Iva Kirac, Daqing Ma, Zhirajr Mokini, Jose Luis Guerrero Orriach, Michael Retsky, Sergio Sandrucci, Wiebke SiekmannLjilja Štefančić, Gina Votta-Vellis, Cara Connolly, Donal Buggy

*Corresponding author for this work

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Abstract

The question of whether anesthetic, analgesic or other perioperative intervention during cancer resection surgery might influence long-term oncologic outcomes has generated much attention over the past 13 years. A wealth of experimental and observational clinical data have been published, but the results of prospective, randomized clinical trials are awaited. The European Union supports a pan-European network of researchers, clinicians and industry partners engaged in this question (COST Action 15204: Euro-Periscope). In this narrative review, members of the Euro-Periscope network briefly summarize the current state of evidence pertaining to the potential effects of the most commonly deployed anesthetic and analgesic techniques and other non-surgical interventions during cancer resection surgery on tumor recurrence or metastasis. View Full-Text
Original languageEnglish
Article number592
JournalCancers
Volume11
Issue number5
Early online date28 Apr 2019
DOIs
Publication statusPublished - May 2019

Keywords

  • cancer
  • anaesthesia
  • analgesia

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    Forget, P., Aguirre, J. A., Bencic, I., Borgeat, A., Cama, A., Condron, C., Eintrei, C., Eroles, P., Gupta, A., Hales, T. G., Ionescu, D., Johnson, M., Kabata, P., Kirac, I., Ma, D., Mokini, Z., Orriach, J. L. G., Retsky, M., Sandrucci, S., ... Buggy, D. (2019). How Anesthetic, Analgesic and Other Non-Surgical Techniques During Cancer Surgery Might Affect Postoperative Oncologic Outcomes: A Summary of Current State of Evidence. Cancers, 11(5), [592]. https://doi.org/10.3390/cancers11050592