Human herpesvirus 8 detection in nasal secretions and saliva

David J. Blackbourn, Evelyne T. Lennette, John Ambroziak, Dan V. Mourich, Jay A. Levy*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

101 Citations (Scopus)

Abstract

The presence of human herpesvirus 8 (HHV-8) was determined by polymerase chain reaction (PCR) in nasal secretions and saliva from 14 HHV-8- seropositive persons, including 8 Kaposi's sarcoma patients: 7 were human immunodeficiency virus type 1-infected, 6 of whom were asymptomatic. HHV-8 was detected in one or both body fluids in 8 (57%) of 14 subjects. Parallel PCR testing revealed the concomitant presence of cytomegalovirus, Epstein- Barr virus, and HHV-6 in various combinations in these body fluids. These data indicate frequent shedding of multiple herpes-viruses in nasal secretions and saliva, particularly in Kaposi's sarcoma patients. Both body fluids are therefore potential sources HHV-8 by nonsexual transmission.

Original languageEnglish
Pages (from-to)213-216
Number of pages4
JournalJournal of Infectious Diseases
Volume177
Issue number1
DOIs
Publication statusPublished - 1998

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