Human herpesvirus 8 seroprevalence among children and adolescents in the United States

Lesley A. Anderson; Yan Li; Barry I. Graubard; Denise Whitby; Georgina Mbisa; Sylvia Tan; James J. Goedert; Eric A. Engels

doi:10.1097/INF.0b013e3181691740

Human herpesvirus 8 seroprevalence among children and adolescents in the United States

Lesley A. Anderson, Yan Li, Barry I. Graubard, Denise Whitby, Georgina Mbisa, Sylvia Tan, James J. Goedert, Eric A. Engels

Applied Health Sciences

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status.

Original language	English
Pages (from-to)	661-664
Number of pages	4
Journal	Pediatric Infectious Disease Journal
Volume	27
Issue number	7
DOIs	https://doi.org/10.1097/INF.0b013e3181691740
Publication status	Published - Jul 2008

Keywords

Adolescents
Asthma
Children
Familial clustering
Hay fever
HHV-8
Human herpesvirus 8
Kaposi sarcomaassociated herpes virus
KSHV
Socioeconomic status
U.S.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/INF.0b013e3181691740

Cite this

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title = "Human herpesvirus 8 seroprevalence among children and adolescents in the United States",

abstract = "We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status.",

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author = "Anderson, {Lesley A.} and Yan Li and Graubard, {Barry I.} and Denise Whitby and Georgina Mbisa and Sylvia Tan and Goedert, {James J.} and Engels, {Eric A.}",

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T1 - Human herpesvirus 8 seroprevalence among children and adolescents in the United States

AU - Anderson, Lesley A.

AU - Li, Yan

AU - Graubard, Barry I.

AU - Whitby, Denise

AU - Mbisa, Georgina

AU - Tan, Sylvia

AU - Goedert, James J.

AU - Engels, Eric A.

PY - 2008/7

Y1 - 2008/7

N2 - We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status.

AB - We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status.

KW - Adolescents

KW - Asthma

KW - Children

KW - Familial clustering

KW - Hay fever

KW - HHV-8

KW - Human herpesvirus 8

KW - Kaposi sarcomaassociated herpes virus

KW - KSHV

KW - Socioeconomic status

KW - U.S.

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AN - SCOPUS:50949101304

SN - 0891-3668

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EP - 664

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 7

ER -

Human herpesvirus 8 seroprevalence among children and adolescents in the United States

Abstract

Keywords

UN SDGs

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