Human herpesvirus 8 seroprevalence among children and adolescents in the United States

Lesley A. Anderson, Yan Li, Barry I. Graubard, Denise Whitby, Georgina Mbisa, Sylvia Tan, James J. Goedert, Eric A. Engels

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We measured human herpesvirus-8 antibodies (K8.1 and orf73 enzyme immunoassays) in 4166 children, aged 6-17 years, in a U.S. cross-sectional survey. Forty-six were K8.1 seropositive (weighted seroprevalence: 1.1%) and 20 were orf73 seropositive (weighted seroprevalence 0.4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status.

Original languageEnglish
Pages (from-to)661-664
Number of pages4
JournalPediatric Infectious Disease Journal
Volume27
Issue number7
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Adolescents
  • Asthma
  • Children
  • Familial clustering
  • Hay fever
  • HHV-8
  • Human herpesvirus 8
  • Kaposi sarcomaassociated herpes virus
  • KSHV
  • Socioeconomic status
  • U.S.

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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