Aphanomyces invadans, the causal agent of Epizootic Ulcerative Syndrome, is a global threat to wild and farmed fish

Nurul Aqilah Iberahim, Franziska Trusch, Pieter van West*

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)
28 Downloads (Pure)

Abstract

Aphanomyces invadans is a eukaryotic pathogen and the causative agent of Epizootic Ulcerative Syndrome (EUS) in fish and is responsible for mortalities of up to 100% in aquaculture. A. invadans was first discovered in Japan in 1971, and since then it has been found in Australia, North America, Southern African countries and Asia. Methods for the correct identification of A. invadans are well established now and involve PCR-based detection and microscopy. However, the pathogenesis of A. invadans is poorly understood. Environmental stress (mainly temperature) and the associated immunocompromised fish seem to induce infections of A. invadans and outbreaks of EUS. Understanding the process of infection in more depth is fundamental for the discovery of novel effective treatments to combat the disease. In this review, we discuss morphological characteristics of A. invadans and its pathogenicity as well as various approaches of treatment.

Original languageEnglish
Pages (from-to)118-130
Number of pages13
JournalFungal Biology Reviews
Volume32
Issue number3
Early online date21 May 2018
DOIs
Publication statusPublished - Jun 2018

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Aphanomyces
Fishes
Aquaculture
North America
Infection
Disease Outbreaks
Virulence
Microscopy
Japan
Polymerase Chain Reaction
Temperature
Mortality
Therapeutics

Keywords

  • Aphanomyces invadans
  • Aquaculture
  • EGA
  • EUS
  • Oomycete

ASJC Scopus subject areas

  • Microbiology

Cite this

Aphanomyces invadans, the causal agent of Epizootic Ulcerative Syndrome, is a global threat to wild and farmed fish. / Iberahim, Nurul Aqilah; Trusch, Franziska; van West, Pieter.

In: Fungal Biology Reviews, Vol. 32, No. 3, 06.2018, p. 118-130.

Research output: Contribution to journalArticle

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