Aphanomyces invadans, the causal agent of Epizootic Ulcerative Syndrome, is a global threat to wild and farmed fish

Nurul Aqilah Iberahim; Franziska Trusch; Pieter van West

doi:10.1016/j.fbr.2018.05.002

Aphanomyces invadans, the causal agent of Epizootic Ulcerative Syndrome, is a global threat to wild and farmed fish

Nurul Aqilah Iberahim, Franziska Trusch, Pieter van West^* (Corresponding Author)

^*Corresponding author for this work

Universiti Malaysia Terengganu

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

169 Downloads (Pure)

Abstract

Aphanomyces invadans is a eukaryotic pathogen and the causative agent of Epizootic Ulcerative Syndrome (EUS) in fish and is responsible for mortalities of up to 100% in aquaculture. A. invadans was first discovered in Japan in 1971, and since then it has been found in Australia, North America, Southern African countries and Asia. Methods for the correct identification of A. invadans are well established now and involve PCR-based detection and microscopy. However, the pathogenesis of A. invadans is poorly understood. Environmental stress (mainly temperature) and the associated immunocompromised fish seem to induce infections of A. invadans and outbreaks of EUS. Understanding the process of infection in more depth is fundamental for the discovery of novel effective treatments to combat the disease. In this review, we discuss morphological characteristics of A. invadans and its pathogenicity as well as various approaches of treatment.

Original language	English
Pages (from-to)	118-130
Number of pages	13
Journal	Fungal Biology Reviews
Volume	32
Issue number	3
Early online date	21 May 2018
DOIs	https://doi.org/10.1016/j.fbr.2018.05.002
Publication status	Published - Jun 2018

Bibliographical note

Acknowledgements
Our work is supported by the University of Aberdeen (PvW); BBSRC (BB/M026566/1 & BB/P020224/1: PvW); BBSRC (BB/N005058/1 & BB/J018333/1: FT & PvW); NERC (NE/P010873/1: PvW) and a PhD scholarship from Ministry of Education Malaysia (NAI).

Keywords

Aphanomyces invadans
Aquaculture
EGA
EUS
Oomycete

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© 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Accepted author manuscript, 874 KBLicence: CC BY-NC-ND

Cite this

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abstract = "Aphanomyces invadans is a eukaryotic pathogen and the causative agent of Epizootic Ulcerative Syndrome (EUS) in fish and is responsible for mortalities of up to 100% in aquaculture. A. invadans was first discovered in Japan in 1971, and since then it has been found in Australia, North America, Southern African countries and Asia. Methods for the correct identification of A. invadans are well established now and involve PCR-based detection and microscopy. However, the pathogenesis of A. invadans is poorly understood. Environmental stress (mainly temperature) and the associated immunocompromised fish seem to induce infections of A. invadans and outbreaks of EUS. Understanding the process of infection in more depth is fundamental for the discovery of novel effective treatments to combat the disease. In this review, we discuss morphological characteristics of A. invadans and its pathogenicity as well as various approaches of treatment.",

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AB - Aphanomyces invadans is a eukaryotic pathogen and the causative agent of Epizootic Ulcerative Syndrome (EUS) in fish and is responsible for mortalities of up to 100% in aquaculture. A. invadans was first discovered in Japan in 1971, and since then it has been found in Australia, North America, Southern African countries and Asia. Methods for the correct identification of A. invadans are well established now and involve PCR-based detection and microscopy. However, the pathogenesis of A. invadans is poorly understood. Environmental stress (mainly temperature) and the associated immunocompromised fish seem to induce infections of A. invadans and outbreaks of EUS. Understanding the process of infection in more depth is fundamental for the discovery of novel effective treatments to combat the disease. In this review, we discuss morphological characteristics of A. invadans and its pathogenicity as well as various approaches of treatment.

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Aphanomyces invadans, the causal agent of Epizootic Ulcerative Syndrome, is a global threat to wild and farmed fish

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Keywords

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