Identification of adults with symptoms suggestive of obstructive airways disease

validation of a postal respiratory questionnaire

Timothy L Frank, Peter I Frank, Jennifer A Cropper, Michelle L Hazell, Philip C Hannaford, Roseanna R McNamee, Sybil Hirsch, Charles A C Pickering

Research output: Contribution to journalArticle

5 Citations (Scopus)
3 Downloads (Pure)

Abstract

Background
Two simples scoring systems for a self-completed postal respiratory questionnaire were developed to identify adults who may have obstructive airways disease. The objective of this study was to validate these scoring systems.

Method
A two-stage design was used. All adults in two practice populations were sent the questionnaire and a stratified random sample of respondents was selected to undergo full clinical evaluation. Three respiratory physicians reviewed the results of each evaluation. A majority decision was reached as to whether the subject merited a trial of obstructive airways disease medication. This clinical decision was compared with two scoring systems based on the questionnaire in order to determine their positive predictive value, sensitivity and specificity.

Results
The PPV (positive predictive value) of the first scoring system was 75.1% (95% CI 68.6–82.3), whilst that of the second system was 82.3% (95% CI 75.9–89.2). The more stringent second system had the greater specificity, 97.1% (95% CI 96.0–98.2) versus 95.3% (95% CI 94.0–96.7), but poorer sensitivity 46.9% (95% CI 33.0–66.8) versus 50.3% (95% CI 35.3–71.6).

Conclusion
This scoring system based on the number of symptoms/risk factors reported via a postal questionnaire could be used to identify adults who would benefit from a trial of treatment for obstructive airways disease.
Original languageEnglish
Article number5
Number of pages6
JournalBMC Family Practice
Volume4
DOIs
Publication statusPublished - 25 Apr 2003

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Surveys and Questionnaires
Physicians
Sensitivity and Specificity
Population
Therapeutics

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Identification of adults with symptoms suggestive of obstructive airways disease : validation of a postal respiratory questionnaire. / Frank, Timothy L; Frank, Peter I; Cropper, Jennifer A; Hazell, Michelle L; Hannaford, Philip C; McNamee, Roseanna R; Hirsch, Sybil; Pickering, Charles A C.

In: BMC Family Practice, Vol. 4, 5, 25.04.2003.

Research output: Contribution to journalArticle

Frank, Timothy L ; Frank, Peter I ; Cropper, Jennifer A ; Hazell, Michelle L ; Hannaford, Philip C ; McNamee, Roseanna R ; Hirsch, Sybil ; Pickering, Charles A C. / Identification of adults with symptoms suggestive of obstructive airways disease : validation of a postal respiratory questionnaire. In: BMC Family Practice. 2003 ; Vol. 4.
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abstract = "BackgroundTwo simples scoring systems for a self-completed postal respiratory questionnaire were developed to identify adults who may have obstructive airways disease. The objective of this study was to validate these scoring systems.MethodA two-stage design was used. All adults in two practice populations were sent the questionnaire and a stratified random sample of respondents was selected to undergo full clinical evaluation. Three respiratory physicians reviewed the results of each evaluation. A majority decision was reached as to whether the subject merited a trial of obstructive airways disease medication. This clinical decision was compared with two scoring systems based on the questionnaire in order to determine their positive predictive value, sensitivity and specificity.ResultsThe PPV (positive predictive value) of the first scoring system was 75.1{\%} (95{\%} CI 68.6–82.3), whilst that of the second system was 82.3{\%} (95{\%} CI 75.9–89.2). The more stringent second system had the greater specificity, 97.1{\%} (95{\%} CI 96.0–98.2) versus 95.3{\%} (95{\%} CI 94.0–96.7), but poorer sensitivity 46.9{\%} (95{\%} CI 33.0–66.8) versus 50.3{\%} (95{\%} CI 35.3–71.6).ConclusionThis scoring system based on the number of symptoms/risk factors reported via a postal questionnaire could be used to identify adults who would benefit from a trial of treatment for obstructive airways disease.",
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AU - Frank, Peter I

AU - Cropper, Jennifer A

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AU - Hannaford, Philip C

AU - McNamee, Roseanna R

AU - Hirsch, Sybil

AU - Pickering, Charles A C

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N2 - BackgroundTwo simples scoring systems for a self-completed postal respiratory questionnaire were developed to identify adults who may have obstructive airways disease. The objective of this study was to validate these scoring systems.MethodA two-stage design was used. All adults in two practice populations were sent the questionnaire and a stratified random sample of respondents was selected to undergo full clinical evaluation. Three respiratory physicians reviewed the results of each evaluation. A majority decision was reached as to whether the subject merited a trial of obstructive airways disease medication. This clinical decision was compared with two scoring systems based on the questionnaire in order to determine their positive predictive value, sensitivity and specificity.ResultsThe PPV (positive predictive value) of the first scoring system was 75.1% (95% CI 68.6–82.3), whilst that of the second system was 82.3% (95% CI 75.9–89.2). The more stringent second system had the greater specificity, 97.1% (95% CI 96.0–98.2) versus 95.3% (95% CI 94.0–96.7), but poorer sensitivity 46.9% (95% CI 33.0–66.8) versus 50.3% (95% CI 35.3–71.6).ConclusionThis scoring system based on the number of symptoms/risk factors reported via a postal questionnaire could be used to identify adults who would benefit from a trial of treatment for obstructive airways disease.

AB - BackgroundTwo simples scoring systems for a self-completed postal respiratory questionnaire were developed to identify adults who may have obstructive airways disease. The objective of this study was to validate these scoring systems.MethodA two-stage design was used. All adults in two practice populations were sent the questionnaire and a stratified random sample of respondents was selected to undergo full clinical evaluation. Three respiratory physicians reviewed the results of each evaluation. A majority decision was reached as to whether the subject merited a trial of obstructive airways disease medication. This clinical decision was compared with two scoring systems based on the questionnaire in order to determine their positive predictive value, sensitivity and specificity.ResultsThe PPV (positive predictive value) of the first scoring system was 75.1% (95% CI 68.6–82.3), whilst that of the second system was 82.3% (95% CI 75.9–89.2). The more stringent second system had the greater specificity, 97.1% (95% CI 96.0–98.2) versus 95.3% (95% CI 94.0–96.7), but poorer sensitivity 46.9% (95% CI 33.0–66.8) versus 50.3% (95% CI 35.3–71.6).ConclusionThis scoring system based on the number of symptoms/risk factors reported via a postal questionnaire could be used to identify adults who would benefit from a trial of treatment for obstructive airways disease.

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