Identifying patients at risk of poor asthma outcomes associated with making inhaler technique errors

Sarah Ann Barbara* (Corresponding Author), Vicky Kritikos, David B. Price, Sinthia Bosnic-Anticevich

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Objectives: Correct inhaler technique is essential to optimal clinical outcomes in asthma patients. The study aim was to use real-life data from the iHARP database to determine patient factors associated with the performance of inhaler technique errors associated with poor asthma outcomes (as identified in the Critikal study) in patients with asthma prescribed the Turbuhaler (TH), Metered Dose Inhaler (MDI), and Accuhaler (AH) device. Methods: This was a retrospective cross-sectional study using the iHARP database, a multinational initiative including questionnaires and technique review. Identification of inhaler technique errors specifically associated with poor asthma outcomes was performed by reference to the Critikal study. Multivariable logistic regression was used to identify demographic and clinical factors associated with ≥ 1 of these errors. Results: Factors significantly associated with ≥ 1 inhaler technique error and worsening asthma outcomes for the TH cohort include female gender, very poor to average self-assessment of inhaler technique; for the MDI cohort, female gender, secondary education, and current smoking status; and, in the AH cohort, lack of inhaler technique review by a trained healthcare professional in the previous twelve months and very poor to average self-assessment of inhaler technique. Conclusions: Numerous specific patient demographic and clinical factors associated with the performance of these errors have been identified, differing according to device. Inhaler technique error associated with poor asthma outcomes is further widespread across devices. Knowledge of these factors and the frequency of their occurence may assist in optimizing device selection and training.

Original languageEnglish
Number of pages12
JournalJournal of Asthma
Early online date31 Mar 2020
DOIs
Publication statusE-pub ahead of print - 31 Mar 2020

Keywords

  • accuhaler
  • Asthma therapy
  • database
  • inhaler technique
  • pressurized metered dose inhaler
  • turbuhaler
  • METERED-DOSE INHALER
  • DRY POWDER INHALERS
  • FREQUENCY
  • GENDER
  • INCORRECT INHALATION TECHNIQUE

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy

Fingerprint Dive into the research topics of 'Identifying patients at risk of poor asthma outcomes associated with making inhaler technique errors'. Together they form a unique fingerprint.

  • Cite this