Imaging Approaches for Dementia

Research output: Contribution to journalLiterature review

10 Citations (Scopus)

Abstract

Brain imaging has progressed from exclusion of rare treatable mass lesions to a specific antemortem diagnosis. MR imaging-derived hippocampal atrophy and WMH are regarded as imaging biomarkers of AD and CVD respectively. Abnormal FP-CIT SPECT or cardiac iodobenzamide SPECT is a useful supportive imaging feature in the diagnosis of DLB. Frontal and/or anterior temporal atrophy and anterior defects on molecular imaging with FDG-PET or perfusion SPECT are characteristic of FTDs. Whole-body FDG-PET may be helpful in patients with rapidly progressing “autoimmune dementias,” and FLAIR and DWI are indicated in suspected CJD. A major role of imaging is in the development of new drugs and less costly biomarkers.
Original languageEnglish
Pages (from-to)1836-1844
Number of pages9
JournalAmerican Journal of Neuroradiology
Volume33
Issue number11
Early online date1 Dec 2011
DOIs
Publication statusPublished - Nov 2012

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