Abstract
Brain imaging has progressed from exclusion of rare treatable mass lesions to a specific antemortem diagnosis. MR imaging-derived hippocampal atrophy and WMH are regarded as imaging biomarkers of AD and CVD respectively. Abnormal FP-CIT SPECT or cardiac iodobenzamide SPECT is a useful supportive imaging feature in the diagnosis of DLB. Frontal and/or anterior temporal atrophy and anterior defects on molecular imaging with FDG-PET or perfusion SPECT are characteristic of FTDs. Whole-body FDG-PET may be helpful in patients with rapidly progressing “autoimmune dementias,” and FLAIR and DWI are indicated in suspected CJD. A major role of imaging is in the development of new drugs and less costly biomarkers.
Original language | English |
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Pages (from-to) | 1836-1844 |
Number of pages | 9 |
Journal | American Journal of Neuroradiology |
Volume | 33 |
Issue number | 11 |
Early online date | 1 Dec 2011 |
DOIs | |
Publication status | Published - Nov 2012 |