Abstract
Immunoglobulin allotype frequencies were determined in well characterised groups of responders (n = 160) and non-responders (n = 32) to Rh(D) antigen immunisation. Allotype frequencies in these groups were compared with frequencies in a normal control population (n = 500). No significant differences in allotype frequencies were observed between the responder and non-responder groups, or when these two groups where compared with a normal control population. These results suggest that the immunoglobulin heavy-chain genes do not influence the anti-Rh(D) immune response.
| Original language | English |
|---|---|
| Pages (from-to) | 88-91 |
| Number of pages | 4 |
| Journal | Experimental and Clinical Immunogenetics |
| Volume | 12 |
| Issue number | 2 |
| Publication status | Published - 1 Jan 1995 |
Keywords
- Female
- Haplotypes
- Humans
- Immunoglobulin Allotypes
- Immunoglobulin G
- Immunoglobulin Gm Allotypes
- Isoantibodies
- Male
- Rh-Hr Blood-Group System