Immunoglobulin allotype frequencies were determined in well characterised groups of responders (n = 160) and non-responders (n = 32) to Rh(D) antigen immunisation. Allotype frequencies in these groups were compared with frequencies in a normal control population (n = 500). No significant differences in allotype frequencies were observed between the responder and non-responder groups, or when these two groups where compared with a normal control population. These results suggest that the immunoglobulin heavy-chain genes do not influence the anti-Rh(D) immune response.
|Number of pages||4|
|Journal||Experimental and Clinical Immunogenetics|
|Publication status||Published - 1 Jan 1995|
- Immunoglobulin Allotypes
- Immunoglobulin G
- Immunoglobulin Gm Allotypes
- Rh-Hr Blood-Group System