Immunohistochemical detection of ERβ in breast cancer

Towards more detailed receptor profiling?

G. P. Skliris, P. J. Carder, M. R.J. Lansdown, V. Speirs*

*Corresponding author for this work

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, immunohistochemical detection of ERβ in archival breast tumours.

Original languageEnglish
Pages (from-to)1095-1098
Number of pages4
JournalBritish Journal of Cancer
Volume84
Issue number8
DOIs
Publication statusPublished - 20 Apr 2001

Fingerprint

Breast Neoplasms
Estrogen Receptors
Messenger RNA
Proteins

Keywords

  • Breast cancer
  • ERβ
  • Formalin-fixed
  • Immunohistochemistry
  • Paraffin-embedded material

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Immunohistochemical detection of ERβ in breast cancer : Towards more detailed receptor profiling? / Skliris, G. P.; Carder, P. J.; Lansdown, M. R.J.; Speirs, V.

In: British Journal of Cancer, Vol. 84, No. 8, 20.04.2001, p. 1095-1098.

Research output: Contribution to journalArticle

Skliris, G. P. ; Carder, P. J. ; Lansdown, M. R.J. ; Speirs, V. / Immunohistochemical detection of ERβ in breast cancer : Towards more detailed receptor profiling?. In: British Journal of Cancer. 2001 ; Vol. 84, No. 8. pp. 1095-1098.
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