Immunohistochemical detection of ERβ in breast cancer: Towards more detailed receptor profiling?

G. P. Skliris; P. J. Carder; M. R.J. Lansdown; V. Speirs

doi:10.1054/bjoc.2001.1721

Immunohistochemical detection of ERβ in breast cancer: Towards more detailed receptor profiling?

G. P. Skliris, P. J. Carder, M. R.J. Lansdown, V. Speirs^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

86 Citations (Scopus)

Abstract

Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, immunohistochemical detection of ERβ in archival breast tumours.

Original language	English
Pages (from-to)	1095-1098
Number of pages	4
Journal	British Journal of Cancer
Volume	84
Issue number	8
DOIs	https://doi.org/10.1054/bjoc.2001.1721
Publication status	Published - 20 Apr 2001
Externally published	Yes

Keywords

Breast cancer
ERβ
Formalin-fixed
Immunohistochemistry
Paraffin-embedded material

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1054/bjoc.2001.1721Licence: CC BY

Cite this

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abstract = "Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, immunohistochemical detection of ERβ in archival breast tumours.",

keywords = "Breast cancer, ERβ, Formalin-fixed, Immunohistochemistry, Paraffin-embedded material",

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AU - Lansdown, M. R.J.

AU - Speirs, V.

PY - 2001/4/20

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AB - Oestrogen receptor (ER) is used routinely to predict endocrine responsiveness in patients with breast cancer. A second ER, ERβ has been described but its significance remains undefined; most studies have described mRNA levels rather than protein expression. Here, we demonstrate for the first time, immunohistochemical detection of ERβ in archival breast tumours.

KW - Breast cancer

KW - ERβ

KW - Formalin-fixed

KW - Immunohistochemistry

KW - Paraffin-embedded material

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Immunohistochemical detection of ERβ in breast cancer: Towards more detailed receptor profiling?

Abstract

Keywords

UN SDGs

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