Impact of age on access site-related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society

Simon G Anderson, Karim Ratib, Phyo K Myint, Bernard Keavney, Chun Shing Kwok, Azfar Zaman, Peter F Ludman, Mark A de Belder, James Nolan, Mamas A Mamas, on behalf of the British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research

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We investigate adoption of the TRA in different age groups and study the relationship between age and access site related outcomes in a national cohort of patients undergoing PCI in the UK. Previous studies have reported conflicting data on radial access site adoption between different age groups, with age an independent predictor of failure of procedures undertaken through the radial approach. Age and access site related outcomes (based on transradial (TRA) and transfemoral (TFA) access) were studied in 469,983 PCI procedures undertaken in the UK from 2006 to 2012 in the age groups; <60, 60-<70, 70-<80, and ≥80 in the British Cardiovascular Intervention Society database. We studied access site practice in 469,983 patients who underwent PCI procedures in the United Kingdom. TRA utilization increased from 17.5% to 65.6% in the age group <60, and 16.6% to 54.5% in the age group ≥80 between 2006 and 2012. TRA was independently associated with decreased 30-day mortality in all age groups (<60: OR 0.64; 95% CI 0.54-0.74, P < 0.0001; 60-<70: OR 0.65; 95% CI 0.57-75, P < 0.0001, 70-<80: OR 0.58 (0.52-0.65, P < 0.0001 and ≥80: OR 0.65 (0.57-0.73, P < 0.0001). Adoption of the TRA for PCI has occurred least in older patients in the UK despite similar associations between TRA use and decreased 30-day mortality observed in all age groups. © 2015 Wiley Periodicals, Inc.

Original languageEnglish
Pages (from-to)965-972
Number of pages8
JournalCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Issue number6
Early online date25 Feb 2015
Publication statusPublished - 15 Nov 2015



  • age
  • access site
  • outcomes
  • PCI

ASJC Scopus subject areas

  • Health Professions(all)

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