Impact of antibiotic restrictions: the physician's perspective

Research output: Contribution to journalEditorial

7 Citations (Scopus)

Abstract

In recent years, there have been worldwide efforts to reduce inappropriate antibiotic prescribing. This has mainly been in response to mounting concerns about the emergence of antimicrobial resistance. Surprisingly, there has been little systematic investigation of the impact of antibiotic restrictions on the complications of infection. It is difficult to address this question using randomised clinical trials in light of the often limited numbers of patients that can be included, who are also often atypical of the broad population of patients receiving antibiotic therapy. Observational data from the UK indicate an association between recent reductions in antibiotic prescribing for lower respiratory tract infection in general practice and an increase in pneumonia mortality. These studies suggest a need for further investigations examining the changing patterns of antibiotic prescribing and their effects on patient outcomes in other countries and in other common infectious diseases. Such studies may provide a useful comparison with the changes observed in lower respiratory tract infection in the UK, and could help to improve antibiotic prescribing practices worldwide. It is also important to study whether associated worse outcomes are limited to certain at-risk groups who should be targeted for care.

Original languageEnglish
Pages (from-to)3-9
Number of pages6
JournalClinical Microbiology and Infection
Volume12
Issue numberSUPPL. 5
DOIs
Publication statusPublished - Jul 2006

Keywords

  • antibiotic resistance
  • community-acquired pneumonia
  • mortality
  • rational antibiotic prescribing
  • review
  • COMMUNITY-ACQUIRED PNEUMONIA
  • C-REACTIVE PROTEIN
  • RESPIRATORY-TRACT INFECTIONS
  • PNEUMOCOCCAL PNEUMONIA
  • CONTROLLED-TRIALS
  • PROGNOSIS
  • SUSCEPTIBILITY
  • GUIDELINES
  • ADMISSIONS
  • MANAGEMENT

Cite this

Impact of antibiotic restrictions: the physician's perspective. / Price, David Brendan.

In: Clinical Microbiology and Infection, Vol. 12, No. SUPPL. 5, 07.2006, p. 3-9.

Research output: Contribution to journalEditorial

@article{6b57a98a61f74c9eaf1f475c4d0375c8,
title = "Impact of antibiotic restrictions: the physician's perspective",
abstract = "In recent years, there have been worldwide efforts to reduce inappropriate antibiotic prescribing. This has mainly been in response to mounting concerns about the emergence of antimicrobial resistance. Surprisingly, there has been little systematic investigation of the impact of antibiotic restrictions on the complications of infection. It is difficult to address this question using randomised clinical trials in light of the often limited numbers of patients that can be included, who are also often atypical of the broad population of patients receiving antibiotic therapy. Observational data from the UK indicate an association between recent reductions in antibiotic prescribing for lower respiratory tract infection in general practice and an increase in pneumonia mortality. These studies suggest a need for further investigations examining the changing patterns of antibiotic prescribing and their effects on patient outcomes in other countries and in other common infectious diseases. Such studies may provide a useful comparison with the changes observed in lower respiratory tract infection in the UK, and could help to improve antibiotic prescribing practices worldwide. It is also important to study whether associated worse outcomes are limited to certain at-risk groups who should be targeted for care.",
keywords = "antibiotic resistance, community-acquired pneumonia, mortality, rational antibiotic prescribing, review, COMMUNITY-ACQUIRED PNEUMONIA, C-REACTIVE PROTEIN, RESPIRATORY-TRACT INFECTIONS, PNEUMOCOCCAL PNEUMONIA, CONTROLLED-TRIALS, PROGNOSIS, SUSCEPTIBILITY, GUIDELINES, ADMISSIONS, MANAGEMENT",
author = "Price, {David Brendan}",
year = "2006",
month = "7",
doi = "10.1111/j.1469-0691.2006.01525.x",
language = "English",
volume = "12",
pages = "3--9",
journal = "Clinical Microbiology and Infection",
issn = "1198-743X",
publisher = "Elsevier",
number = "SUPPL. 5",

}

TY - JOUR

T1 - Impact of antibiotic restrictions: the physician's perspective

AU - Price, David Brendan

PY - 2006/7

Y1 - 2006/7

N2 - In recent years, there have been worldwide efforts to reduce inappropriate antibiotic prescribing. This has mainly been in response to mounting concerns about the emergence of antimicrobial resistance. Surprisingly, there has been little systematic investigation of the impact of antibiotic restrictions on the complications of infection. It is difficult to address this question using randomised clinical trials in light of the often limited numbers of patients that can be included, who are also often atypical of the broad population of patients receiving antibiotic therapy. Observational data from the UK indicate an association between recent reductions in antibiotic prescribing for lower respiratory tract infection in general practice and an increase in pneumonia mortality. These studies suggest a need for further investigations examining the changing patterns of antibiotic prescribing and their effects on patient outcomes in other countries and in other common infectious diseases. Such studies may provide a useful comparison with the changes observed in lower respiratory tract infection in the UK, and could help to improve antibiotic prescribing practices worldwide. It is also important to study whether associated worse outcomes are limited to certain at-risk groups who should be targeted for care.

AB - In recent years, there have been worldwide efforts to reduce inappropriate antibiotic prescribing. This has mainly been in response to mounting concerns about the emergence of antimicrobial resistance. Surprisingly, there has been little systematic investigation of the impact of antibiotic restrictions on the complications of infection. It is difficult to address this question using randomised clinical trials in light of the often limited numbers of patients that can be included, who are also often atypical of the broad population of patients receiving antibiotic therapy. Observational data from the UK indicate an association between recent reductions in antibiotic prescribing for lower respiratory tract infection in general practice and an increase in pneumonia mortality. These studies suggest a need for further investigations examining the changing patterns of antibiotic prescribing and their effects on patient outcomes in other countries and in other common infectious diseases. Such studies may provide a useful comparison with the changes observed in lower respiratory tract infection in the UK, and could help to improve antibiotic prescribing practices worldwide. It is also important to study whether associated worse outcomes are limited to certain at-risk groups who should be targeted for care.

KW - antibiotic resistance

KW - community-acquired pneumonia

KW - mortality

KW - rational antibiotic prescribing

KW - review

KW - COMMUNITY-ACQUIRED PNEUMONIA

KW - C-REACTIVE PROTEIN

KW - RESPIRATORY-TRACT INFECTIONS

KW - PNEUMOCOCCAL PNEUMONIA

KW - CONTROLLED-TRIALS

KW - PROGNOSIS

KW - SUSCEPTIBILITY

KW - GUIDELINES

KW - ADMISSIONS

KW - MANAGEMENT

U2 - 10.1111/j.1469-0691.2006.01525.x

DO - 10.1111/j.1469-0691.2006.01525.x

M3 - Editorial

VL - 12

SP - 3

EP - 9

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

SN - 1198-743X

IS - SUPPL. 5

ER -