In-vitro validation of a novel model-based approach to the measurement of arterial blood flow waveforms from dynamic digital x-ray images

K. Rhode, G. Ennew, T. Lambrou, A. Seifalian, D. Hawkes

Research output: Chapter in Book/Report/Conference proceedingPublished conference contribution

4 Citations (Scopus)

Abstract

We have developed a blood flow waveform shape model using principal component analysis (PCA) and applied this to our existing concentration-distance curve matching technique for the extraction of flow waveforms from dynamic digital x-ray images. The aim of the study was to validate the system using a moving-vessel flow phantom. Instantaneous recording of flow from an electromagnetic flow meter (EMF) provided the “gold standard” measurement. A model waveform was constructed from 256 previously recorded waveforms from the EMF using PCA. Flow waveforms were extracted from parametric images derived from dynamic x-ray data by finding the parameters of the shape model that minimized the mean value of our cost function. The computed waveforms were compared to the EMF recordings. The model-based approach produced narrower limits of agreement with the EMF data than our previously developed algorithms and, in the presence of increasing noise in the parametric images, it out-performed the other algorithms.
Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention
Subtitle of host publicationMICCAI 2001
EditorsW J Niessen, M. A Viergever
Place of PublicationBerlin
PublisherSpringer
Pages291-300
Number of pages10
Volume2208
DOIs
Publication statusPublished - 2001
EventMedical Image Computing and Computer-Assisted Intervention: 4th International Conference - Utrecht, The Netherlands, Utrecht, Netherlands
Duration: 14 Oct 200117 Oct 2001

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
PublisherSpringer Verlag
ISSN (Print)0302-9743

Conference

ConferenceMedical Image Computing and Computer-Assisted Intervention
Abbreviated titleMICCAI 2001
Country/TerritoryNetherlands
CityUtrecht
Period14/10/0117/10/01

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