Abstract
Implant-associated infection, a serious medical issue, is caused by the adhesion of bacteria to the surface of biomaterials; for this process the surface roughness is an important property. Surface nanotopography of medical implant devices can control the extent of bacterial attachment by modifying the surface morphology; to this end a model is introduced to facilitate the analysis of a nanoscale smooth surface subject to mechanical loading and in vivo corrosion. At nanometre scale rough surface promotes friction, hence reduces the mobility of the bacteria; this sessile environment expedites the biofilm growth. This manuscript derives the controlling equation for surface roughness evolution for metallic implant subject to in-plane stresses, and predicts the in vivo roughness changes within 6 hours of continued mechanical loading at different stress level. This paper provides analytic tool and theoretical information for surface nanotopography of medical implant devices.
Original language | English |
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Pages (from-to) | 430-440 |
Number of pages | 11 |
Journal | Journal of the Mechanics and Physics of Solids |
Volume | 95 |
Early online date | 25 May 2016 |
DOIs | |
Publication status | Published - 31 Oct 2016 |
Keywords
- stressed implant
- surface roughness
- in vivo