Inactivation of anandamide signaling: A continuing Debate

H. Khairy, Wael E Houssen

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)
5 Downloads (Pure)

Abstract

Since the first endocannabinoid anandamide was identified in 1992, extensive research has been conducted to characterize the elements of the tightly controlled endocannabinoid signaling system. While it was established that the activity of endocannabinoids are terminated by a two-step process that includes cellular uptake and degradation, there is still a continuing debate about the mechanistic role of these rocesses in inactivating anandamide signals.
Original languageEnglish
Pages (from-to)3355-3370
Number of pages16
JournalPharmaceuticals
Volume3
Issue number11
DOIs
Publication statusPublished - 1 Jan 2010

Keywords

  • endocannabinoid inactivation
  • anandamide
  • ethanolamine

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