With great interest we read the recent article from Iwai et al. entitled "Repeat-dose intravenous tranexamic acid further decreases blood loss in total knee arthroplasty" . The authors report on the use of tranexamic acid to reduce the rate of peri-operative blood transfusions in patients undergoing total knee arthroplasty (TKA). We agree fully with the authors that the development of strategies to reduce blood loss and the rate of peri-operative transfusions is imperative in modern TKA surgery. However, we have some concerns related to the published work.
- Total Knee Arthroplasty
- Tranexamic Acid
- Allogenic Transfusion
- Genicular Artery
Forget, P., Grosu, I., & Thienpont, E. (2013). Inadequate methodology renders results on the use of tranexamic acid inconclusive. The Journal of Arthroplasty, 37(7), 1417-1418. https://doi.org/10.1007/s00264-013-1889-2