Incidence, Predictors, and Outcomes of Major Bleeding Among Patients Hospitalized with Acute Heart Failure.

D. Abramovich, Ofer Kobo, E. Gorodeski , JS Rana, MN Walsh , S. Gevaert, P. Parwani , Phyo Kyaw Myint, A.J Sauer, Mamas A Mamas* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
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Abstract

Acute heart failure (AHF) is a common etiology of hospitalization and is associated with morbidity, including bleeding. In this study, the authors sought to assess the incidence, types, and associates of major bleeding in patients hospitalized with AHF. The National Inpatient Sample from October 2015 to December 2018 was used to identify patients with AHF. The incidence of common bleeding etiologies, and patient demographics, co-morbidities, associated acute cardiac diagnoses, and invasive procedures, were identified. The multivariable logistic regression was used to identify predictors of bleeding and the association of bleeding episodes with inpatient mortality. During the study period, 1,106,634 patients were admitted with a primary diagnosis of AHF, of whom 58,955 (5.3%) had an episode of bleeding. Common bleeding sources were gastrointestinal (25.7%), hematuria (24%), respiratory (23.6%), and procedure-related bleeding (2.5%). Major bleeding was more common in patients with AHF with preserved ejection fraction (odds ratio 1.14, confidence interval 1.12 to 1.16, p
Original languageEnglish
Pages (from-to)59-65
Number of pages7
JournalThe American Journal of Cardiology
Volume191
Early online date12 Jan 2023
DOIs
Publication statusPublished - 15 Mar 2023

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