Abstract
A boy with the cutaneous lesions of incontinentia pigmenti is described. Chromosomal analysis revealed the 47,XXY karyotype of Klinefelter's syndrome. Since incontinentia pigmenti trait is usually lethal in males, the possibility of the second X chromosome protecting against fetal death is discussed.
Original language | English |
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Pages (from-to) | 439-441 |
Number of pages | 3 |
Journal | Journal of Medical Genetics |
Volume | 24 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1 Jul 1987 |
Keywords
- Genes, Dominant
- Genes, Lethal
- Humans
- Incontinentia Pigmenti
- Infant
- Karyotyping
- Klinefelter Syndrome
- Linkage (Genetics)
- Male
- Pigmentation Disorders
- X Chromosome