Intracluster correlation coefficients in cluster randomized trials: empirical insights into how should they be reported

Marion K Campbell, Jeremy M Grimshaw, Diana R Elbourne

Research output: Contribution to journalArticle

67 Citations (Scopus)
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Abstract

BACKGROUND: Increasingly, researchers are recognizing that there are many situations where the use of a cluster randomized trial may be more appropriate than an individually randomized trial. Similarly, the need for appropriate standards of reporting of cluster trials is more widely acknowledged.
METHODS: In this paper, we describe the results of a survey to inform the appropriate reporting of the intracluster correlation coefficient (ICC)--the statistical measure of the clustering effect associated with a cluster randomized trial.
RESULTS: We identified three dimensions that should be considered when reporting an ICC--a description of the dataset (including characteristics of the outcome and the intervention), information on how the ICC was calculated, and information on the precision of the ICC.
CONCLUSIONS: This paper demonstrates the development of a framework for the reporting of ICCs. If adopted into routine practice, it has the potential to facilitate the interpretation of the cluster trial being reported and should help the development of new trials in the area.
Original languageEnglish
Article number9
Number of pages5
JournalBMC Medical Research Methodology
Volume4
DOIs
Publication statusPublished - 28 Apr 2004

Keywords

  • cluster analysis
  • statistical data interpretation
  • empirical research
  • humans
  • randomized controlled trials as topic
  • sample size
  • standards

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