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Abstract
The study of consummatory responses during food intake represents a unique opportunity to investigate the physiological, psychological and neurobiological processes that control ingestive behavior. Recording the occurrence and temporal organization of individual licks across consumption, also called lickometry, yields a rich data set that can be analyzed to dissect consummatory responses into different licking patterns. These patterns, divided into trains of licks separated by pauses, have been used to deconstruct the many influences on consumption, such as palatability evaluation, incentive properties, and post-ingestive processes. In this review, we describe commonly used definitions of licking patterns and how various studies have defined and measured these. We then discuss how licking patterns can be used to investigate the impact of different physiological need states on processes governing ingestive behavior. We also present new data showing how licking patterns are changed in an animal model of protein appetite and how this may guide food choice in different protein-associated hedonic and homeostatic states. Thus, recording lick microstructure can be achieved relatively easily and represents a useful tool to provide insights, beyond the measurement of total intake, into the multiple factors influencing ingestive behavior.
Original language | English |
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Pages (from-to) | 155-166 |
Number of pages | 12 |
Journal | Neuroscience |
Volume | 447 |
Early online date | 1 Nov 2019 |
DOIs | |
Publication status | Published - 1 Nov 2020 |
Bibliographical note
Acknowledgements: We would like to thank Michelle Murphy, Giulia Chiacchierini, and Eelke Snoeren for collecting some of the original data that were re-analyzed in this manuscript and Gonzalo Urcelay for helpful comments on the manuscript. We would also like to acknowledge the help and support from the staff of the Division of Biomedical Services, Preclinical Research Facility, University of Leicester, for technical support and the care of experimental animals.Data availability: Upon publication, all data analyzed in this paper will be available at the following address: https://doi.org/10.25392/leicester.data.9248558.
Funding: This work was supported by the Biotechnology and Biological Sciences Research Council [grant # BB/M007391/1 to J.E.M.], the European Commission [grant # GA 631404 to J.E.M.], and The Leverhulme Trust [grant # RPG-2017-417 to J.E.M.].
Keywords
- appetitive
- consummatory
- lick microstructure
- palatability
- taste
- DEPRIVED RATS LICKING
- REWARD EVALUATION
- D2-LIKE RECEPTORS
- TASTE
- NUCLEUS-ACCUMBENS
- DOPAMINE D1-LIKE
- FOOD-DEPRIVATION
- CONDITIONED ENHANCEMENT
- INGESTIVE BEHAVIOR
- APPETITE
Fingerprint
Dive into the research topics of 'Investigating the Effect of Physiological Need States on Palatability and Motivation Using Microstructural Analysis of Licking'. Together they form a unique fingerprint.Activities
- 2 Presentation
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Impact of protein appetite on the dopamine mesolimbic system
Fabien Naneix (Speaker), Giulia Chiacchierini (Author), Kate Z. Peters (Author), Eelke M. S. Snoeren (Author) & James E. McCutcheon (Speaker)
23 Oct 2019Activity: Disseminating Research › Presentation
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Protein appetite drives VTA neural activity
Fabien Naneix (Speaker)
22 Sept 2019Activity: Disseminating Research › Presentation