Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry

Frithjof C. Kuepper, Lucy J. Carpenter, Gordon B. McFiggans, Carl J. Palmer, Tim J. Waite, Eva-Maria Boneberg, Sonja Woitsch, Markus Weiller, Rafael Abela, Daniel Grolimund, Philippe Potin, Alison Butler, George W. Luther, Peter M. H. Kroneck, Wolfram Meyer-Klaucke, Martin C. Feiters

Research output: Contribution to journalArticle

208 Citations (Scopus)

Abstract

Brown algae of the Laminariales (kelps) are the strongest accumulators of iodine among living organisms. They represent a major pump in the global biogeochemical cycle of iodine and, in particular, the major source of iodocarbons in the coastal atmosphere. Nevertheless, the chemical state and biological significance of accumulated iodine have remained unknown to this date. Using x-ray absorption spectroscopy, we show that the accumulated form is iodide, which readily scavenges a variety of reactive oxygen species (ROS). We propose here that its biological role is that of an inorganic antioxidant, the first to be described in a living system. Upon oxidative stress, iodide is effluxed. On the thallus surface and in the apoplast, iodide detoxifies both aqueous oxidants and ozone, the latter resulting in the release of high levels of molecular iodine and the consequent formation of hygroscopic iodine oxides leading to particles, which are precursors to cloud condensation nuclei. In a complementary set of experiments using a heterologous system, iodide was found to effectively scavenge ROS in human blood cells.

Original languageEnglish
Pages (from-to)6954-6958
Number of pages5
JournalPNAS
Volume105
Issue number19
Early online date5 May 2008
DOIs
Publication statusPublished - 13 May 2008

Keywords

  • algae
  • laminaria
  • X-ray absorption spectroscopy
  • Cathodic stripping square wave voltammetry

Cite this

Kuepper, F. C., Carpenter, L. J., McFiggans, G. B., Palmer, C. J., Waite, T. J., Boneberg, E-M., ... Feiters, M. C. (2008). Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry. PNAS, 105(19), 6954-6958. https://doi.org/10.1073/pnas.0709959105

Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry. / Kuepper, Frithjof C.; Carpenter, Lucy J.; McFiggans, Gordon B.; Palmer, Carl J.; Waite, Tim J.; Boneberg, Eva-Maria; Woitsch, Sonja; Weiller, Markus; Abela, Rafael; Grolimund, Daniel; Potin, Philippe; Butler, Alison; Luther, George W.; Kroneck, Peter M. H.; Meyer-Klaucke, Wolfram; Feiters, Martin C.

In: PNAS, Vol. 105, No. 19, 13.05.2008, p. 6954-6958.

Research output: Contribution to journalArticle

Kuepper, FC, Carpenter, LJ, McFiggans, GB, Palmer, CJ, Waite, TJ, Boneberg, E-M, Woitsch, S, Weiller, M, Abela, R, Grolimund, D, Potin, P, Butler, A, Luther, GW, Kroneck, PMH, Meyer-Klaucke, W & Feiters, MC 2008, 'Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry', PNAS, vol. 105, no. 19, pp. 6954-6958. https://doi.org/10.1073/pnas.0709959105
Kuepper FC, Carpenter LJ, McFiggans GB, Palmer CJ, Waite TJ, Boneberg E-M et al. Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry. PNAS. 2008 May 13;105(19):6954-6958. https://doi.org/10.1073/pnas.0709959105
Kuepper, Frithjof C. ; Carpenter, Lucy J. ; McFiggans, Gordon B. ; Palmer, Carl J. ; Waite, Tim J. ; Boneberg, Eva-Maria ; Woitsch, Sonja ; Weiller, Markus ; Abela, Rafael ; Grolimund, Daniel ; Potin, Philippe ; Butler, Alison ; Luther, George W. ; Kroneck, Peter M. H. ; Meyer-Klaucke, Wolfram ; Feiters, Martin C. / Iodide accumulation provides kelp with an inorganic antioxidant impacting atmospheric chemistry. In: PNAS. 2008 ; Vol. 105, No. 19. pp. 6954-6958.
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AU - Weiller, Markus

AU - Abela, Rafael

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AU - Potin, Philippe

AU - Butler, Alison

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AB - Brown algae of the Laminariales (kelps) are the strongest accumulators of iodine among living organisms. They represent a major pump in the global biogeochemical cycle of iodine and, in particular, the major source of iodocarbons in the coastal atmosphere. Nevertheless, the chemical state and biological significance of accumulated iodine have remained unknown to this date. Using x-ray absorption spectroscopy, we show that the accumulated form is iodide, which readily scavenges a variety of reactive oxygen species (ROS). We propose here that its biological role is that of an inorganic antioxidant, the first to be described in a living system. Upon oxidative stress, iodide is effluxed. On the thallus surface and in the apoplast, iodide detoxifies both aqueous oxidants and ozone, the latter resulting in the release of high levels of molecular iodine and the consequent formation of hygroscopic iodine oxides leading to particles, which are precursors to cloud condensation nuclei. In a complementary set of experiments using a heterologous system, iodide was found to effectively scavenge ROS in human blood cells.

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