Is there a rationale for an anesthesiologist's role against cancer recurrence?

P. Forget* (Corresponding Author), P.G. Coulie, M. Retsky, R. Demicheli, J.-P. Machiels, M. De Kock

*Corresponding author for this work

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Growth of tumors can accelerate during the peri-operative period. Accordingly, early relapse of cancer occurs in some patients during the first two postoperative years. Temporal and biologic analyses of cancer pathophysiology suggest a link between peri-operative pathophysiological changes and acceleration of tumor growth. Understanding the role of inflammation and its consequences (i.e., immune response, growth factors, dissemination of tumor cells) could lead to define a role of anesthesiologists in reducing cancer recurrence following surgery. We argue for peri-operative pharmacological interventions to reduce cancer relapse, with a focus on non-steroidal anti-inflammatory drugs.
Original languageEnglish
Pages (from-to)15-24
Number of pages10
JournalActa Anaesthesiologica Belgica
Volume64
Issue number1
Publication statusPublished - Mar 2013

Keywords

  • inflammation
  • non-steroidal anti-inflammatory drugs
  • postoperative cancer recurrence

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    Forget, P., Coulie, P. G., Retsky, M., Demicheli, R., Machiels, J-P., & De Kock, M. (2013). Is there a rationale for an anesthesiologist's role against cancer recurrence? Acta Anaesthesiologica Belgica, 64(1), 15-24.