Isotope ratio measurements in biological tissues using LA-ICP-MS- possibilities, limitations, and perspectives

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Abstract

This article describes the advantages and possibilities of using LA-ICP-MS for isotope ratio measurements, briefly comparing quadrupole, sector-field and multi-collector systems. It also discusses problems and limitations of the respective set-ups. A special focus lies on biological samples from stable isotope tracer experiments and on spatially resolved isotope ratio measurements including imaging of isotope ratios. The article explores if there are valid reasons why until now almost no one used LA-ICP-MS to image isotope ratios. It wants to encourage the ICP-MS community to realise the potential of using LA-ICP-MS for isotope ratio measurements in biological samples and to hopefully spur further developments and applications.
Original languageEnglish
Pages (from-to)1367-1371
Number of pages5
JournalJournal of Analytical Atomic Spectrometry
Volume28
Issue number9
Early online date21 May 2013
DOIs
Publication statusPublished - 1 Sep 2013

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Isotopes
Tissue
Imaging techniques
Experiments

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