It's about time for neural crest

Stefan Hoppler, Grant N. Wheeler

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

What has made vertebrates so successful has been the evolution of their superior sensory organs, a more sophisticated organization of the brain, and—eventually—toothed powerful jaws, which gradually supported an ecological shift from passive filter feeding to a more active predatory lifestyle. Building this “new head” in vertebrate embryos relies on an elite group of cells called the neural crest (1). Indeed, the English developmental biologist Peter Thorogood famously recounted that as a young scientist he was told by a senior professor (in an authoritative tone), “The only interesting thing about vertebrates is the neural crest” (2). On page 1332 of this issue, Buitrago-Delgado et al. (3) provide further support for this bold statement in demonstrating that neural crest cells uniquely retain pluripotent stem cell programming until later in development than the three classic germ layers.
Original languageEnglish
Pages (from-to)1316-1317
Number of pages2
JournalScience
Volume348
Issue number6241
Early online date30 Apr 2015
DOIs
Publication statusPublished - 19 Jun 2015

Fingerprint

Neural Crest
Vertebrates
Germ Layers
Pluripotent Stem Cells
Jaw
Life Style
Embryonic Structures
Head
Brain

Keywords

  • Neural Crest

Cite this

It's about time for neural crest. / Hoppler, Stefan; Wheeler, Grant N.

In: Science, Vol. 348, No. 6241, 19.06.2015, p. 1316-1317 .

Research output: Contribution to journalArticle

Hoppler, S & Wheeler, GN 2015, 'It's about time for neural crest' Science, vol. 348, no. 6241, pp. 1316-1317 . https://doi.org/10.1126/science.aab2719
Hoppler, Stefan ; Wheeler, Grant N. / It's about time for neural crest. In: Science. 2015 ; Vol. 348, No. 6241. pp. 1316-1317 .
@article{350e5bf9ec7e442c8f838b11ad90623a,
title = "It's about time for neural crest",
abstract = "What has made vertebrates so successful has been the evolution of their superior sensory organs, a more sophisticated organization of the brain, and—eventually—toothed powerful jaws, which gradually supported an ecological shift from passive filter feeding to a more active predatory lifestyle. Building this “new head” in vertebrate embryos relies on an elite group of cells called the neural crest (1). Indeed, the English developmental biologist Peter Thorogood famously recounted that as a young scientist he was told by a senior professor (in an authoritative tone), “The only interesting thing about vertebrates is the neural crest” (2). On page 1332 of this issue, Buitrago-Delgado et al. (3) provide further support for this bold statement in demonstrating that neural crest cells uniquely retain pluripotent stem cell programming until later in development than the three classic germ layers.",
keywords = "Neural Crest",
author = "Stefan Hoppler and Wheeler, {Grant N.}",
year = "2015",
month = "6",
day = "19",
doi = "10.1126/science.aab2719",
language = "English",
volume = "348",
pages = "1316--1317",
journal = "Science",
issn = "0036-8075",
publisher = "AMER ASSOC ADVANCEMENT SCIENCE",
number = "6241",

}

TY - JOUR

T1 - It's about time for neural crest

AU - Hoppler, Stefan

AU - Wheeler, Grant N.

PY - 2015/6/19

Y1 - 2015/6/19

N2 - What has made vertebrates so successful has been the evolution of their superior sensory organs, a more sophisticated organization of the brain, and—eventually—toothed powerful jaws, which gradually supported an ecological shift from passive filter feeding to a more active predatory lifestyle. Building this “new head” in vertebrate embryos relies on an elite group of cells called the neural crest (1). Indeed, the English developmental biologist Peter Thorogood famously recounted that as a young scientist he was told by a senior professor (in an authoritative tone), “The only interesting thing about vertebrates is the neural crest” (2). On page 1332 of this issue, Buitrago-Delgado et al. (3) provide further support for this bold statement in demonstrating that neural crest cells uniquely retain pluripotent stem cell programming until later in development than the three classic germ layers.

AB - What has made vertebrates so successful has been the evolution of their superior sensory organs, a more sophisticated organization of the brain, and—eventually—toothed powerful jaws, which gradually supported an ecological shift from passive filter feeding to a more active predatory lifestyle. Building this “new head” in vertebrate embryos relies on an elite group of cells called the neural crest (1). Indeed, the English developmental biologist Peter Thorogood famously recounted that as a young scientist he was told by a senior professor (in an authoritative tone), “The only interesting thing about vertebrates is the neural crest” (2). On page 1332 of this issue, Buitrago-Delgado et al. (3) provide further support for this bold statement in demonstrating that neural crest cells uniquely retain pluripotent stem cell programming until later in development than the three classic germ layers.

KW - Neural Crest

U2 - 10.1126/science.aab2719

DO - 10.1126/science.aab2719

M3 - Article

VL - 348

SP - 1316

EP - 1317

JO - Science

JF - Science

SN - 0036-8075

IS - 6241

ER -