Abstract
Biochemical studies have shown that a proportion of schizophrenics have an abnormal fatty acid composition in their red blood-cell membrane phospholipids and it has been suggested that this might be due to altered levels of the enzyme phospholipase A2 (PLA2). A recent report indicated that there was an association between schizophrenia and alleles of a poly-A repeat polymorphism close to the 5' end of the PLA2 gene. We report the analysis of this polymorphism in a series of 58 schizophrenic patients and 56 controls and find no evidence for allelic association.
Original language | English |
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Pages (from-to) | 111-114 |
Number of pages | 4 |
Journal | Psychiatric Genetics |
Volume | 7 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jan 1997 |
Keywords
- Association
- Genetics
- Phospholipase
- Phospholipids
- PLA2
- Schizophrenia