Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats

Silvia Gratz, M. Taubel, R. O. Juvonen, M. Viluksela, P. C. Turner, H. Mykkanen, H. El-Nezami

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Abstract

In this study, the modulation of aflatoxin B-1 (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.

Original languageEnglish
Pages (from-to)7398-7400
Number of pages3
JournalApplied and Environmental Microbiology
Volume72
Issue number11
DOIs
Publication statusPublished - Nov 2006

Keywords

  • lactic-acid bacteria
  • dairy strains
  • remove aflatoxin
  • in-vitro
  • ability
  • metabolism
  • bind
  • propionibacterium
  • hepatotoxicity
  • intervention

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