Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats

Silvia Gratz, M. Taubel, R. O. Juvonen, M. Viluksela, P. C. Turner, H. Mykkanen, H. El-Nezami

Research output: Contribution to journalArticle

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Abstract

In this study, the modulation of aflatoxin B-1 (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.

Original languageEnglish
Pages (from-to)7398-7400
Number of pages3
JournalApplied and Environmental Microbiology
Volume72
Issue number11
DOIs
Publication statusPublished - Nov 2006

Keywords

  • lactic-acid bacteria
  • dairy strains
  • remove aflatoxin
  • in-vitro
  • ability
  • metabolism
  • bind
  • propionibacterium
  • hepatotoxicity
  • intervention

Cite this

Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats. / Gratz, Silvia; Taubel, M.; Juvonen, R. O.; Viluksela, M.; Turner, P. C.; Mykkanen, H.; El-Nezami, H.

In: Applied and Environmental Microbiology, Vol. 72, No. 11, 11.2006, p. 7398-7400.

Research output: Contribution to journalArticle

Gratz, Silvia ; Taubel, M. ; Juvonen, R. O. ; Viluksela, M. ; Turner, P. C. ; Mykkanen, H. ; El-Nezami, H. / Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats. In: Applied and Environmental Microbiology. 2006 ; Vol. 72, No. 11. pp. 7398-7400.
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AU - Turner, P. C.

AU - Mykkanen, H.

AU - El-Nezami, H.

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KW - in-vitro

KW - ability

KW - metabolism

KW - bind

KW - propionibacterium

KW - hepatotoxicity

KW - intervention

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