Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats

Silvia Gratz; M. Taubel; R. O. Juvonen; M. Viluksela; P. C. Turner; H. Mykkanen; H. El-Nezami

doi:10.1128/AEM.01348-06

Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats

Silvia Gratz, M. Taubel, R. O. Juvonen, M. Viluksela, P. C. Turner, H. Mykkanen, H. El-Nezami

The Rowett Institute of Nutrition and Health

Research output: Contribution to journal › Article › peer-review

96 Citations (Scopus)

Abstract

In this study, the modulation of aflatoxin B-1 (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.

Original language	English
Pages (from-to)	7398-7400
Number of pages	3
Journal	Applied and Environmental Microbiology
Volume	72
Issue number	11
DOIs	https://doi.org/10.1128/AEM.01348-06
Publication status	Published - Nov 2006

Keywords

lactic-acid bacteria
dairy strains
remove aflatoxin
in-vitro
ability
metabolism
bind
propionibacterium
hepatotoxicity
intervention

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title = "Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats",

abstract = "In this study, the modulation of aflatoxin B-1 (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.",

keywords = "lactic-acid bacteria, dairy strains, remove aflatoxin, in-vitro, ability, metabolism, bind, propionibacterium, hepatotoxicity, intervention",

author = "Silvia Gratz and M. Taubel and Juvonen, {R. O.} and M. Viluksela and Turner, {P. C.} and H. Mykkanen and H. El-Nezami",

year = "2006",

month = nov,

doi = "10.1128/AEM.01348-06",

language = "English",

volume = "72",

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journal = "Applied and Environmental Microbiology",

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TY - JOUR

T1 - Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats

AU - Gratz, Silvia

AU - Taubel, M.

AU - Juvonen, R. O.

AU - Viluksela, M.

AU - Turner, P. C.

AU - Mykkanen, H.

AU - El-Nezami, H.

PY - 2006/11

Y1 - 2006/11

N2 - In this study, the modulation of aflatoxin B-1 (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.

AB - In this study, the modulation of aflatoxin B-1 (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.

KW - lactic-acid bacteria

KW - dairy strains

KW - remove aflatoxin

KW - in-vitro

KW - ability

KW - metabolism

KW - bind

KW - propionibacterium

KW - hepatotoxicity

KW - intervention

U2 - 10.1128/AEM.01348-06

DO - 10.1128/AEM.01348-06

M3 - Article

SN - 0099-2240

VL - 72

SP - 7398

EP - 7400

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 11

ER -

Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B-1 in rats

Abstract

Keywords

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