Lifestyle behaviours and quality-adjusted life years in middle and older age

Phyo K Myint; Richard D Smith; Robert N Luben; Paul G Surtees; Nicholas W J Wainwright; Nicholas J Wareham; Kay-Tee Khaw

doi:10.1093/ageing/afr058

Lifestyle behaviours and quality-adjusted life years in middle and older age

Phyo K Myint, Richard D Smith, Robert N Luben, Paul G Surtees, Nicholas W J Wainwright, Nicholas J Wareham, Kay-Tee Khaw

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

OBJECTIVE: to examine the relationship between combined lifestyle behaviours and quality-adjusted life years (QALYs) in a general population.

METHODS: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level ≥50 µmol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007).

RESULTS: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs.

CONCLUSION: our findings support the view that modifiable lifestyle factors are an important component in health improvement.

Original language	English
Pages (from-to)	589-955
Number of pages	7
Journal	Age and Ageing
Volume	40
Issue number	5
Early online date	26 May 2011
DOIs	https://doi.org/10.1093/ageing/afr058
Publication status	Published - Sept 2011

Keywords

adult
age factors
aged
aging
alcohol drinking
chi-square distribution
diet
England
female
fruit
health surveys
humans
life expectancy
life style
male
middle aged
models, statistical
prospective studies
quality-adjusted life years
risk reduction behavior
smoking
surveys and questionnaires
vegetables

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/ageing/afr058

Cite this

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title = "Lifestyle behaviours and quality-adjusted life years in middle and older age",

abstract = "OBJECTIVE: to examine the relationship between combined lifestyle behaviours and quality-adjusted life years (QALYs) in a general population.METHODS: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level ≥50 µmol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007).RESULTS: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs.CONCLUSION: our findings support the view that modifiable lifestyle factors are an important component in health improvement.",

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author = "Myint, {Phyo K} and Smith, {Richard D} and Luben, {Robert N} and Surtees, {Paul G} and Wainwright, {Nicholas W J} and Wareham, {Nicholas J} and Kay-Tee Khaw",

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doi = "10.1093/ageing/afr058",

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AU - Myint, Phyo K

AU - Smith, Richard D

AU - Luben, Robert N

AU - Surtees, Paul G

AU - Wainwright, Nicholas W J

AU - Wareham, Nicholas J

AU - Khaw, Kay-Tee

PY - 2011/9

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N2 - OBJECTIVE: to examine the relationship between combined lifestyle behaviours and quality-adjusted life years (QALYs) in a general population.METHODS: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level ≥50 µmol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007).RESULTS: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs.CONCLUSION: our findings support the view that modifiable lifestyle factors are an important component in health improvement.

AB - OBJECTIVE: to examine the relationship between combined lifestyle behaviours and quality-adjusted life years (QALYs) in a general population.METHODS: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level ≥50 µmol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007).RESULTS: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was ∼11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs.CONCLUSION: our findings support the view that modifiable lifestyle factors are an important component in health improvement.

KW - adult

KW - age factors

KW - aged

KW - aging

KW - alcohol drinking

KW - chi-square distribution

KW - diet

KW - England

KW - female

KW - fruit

KW - health surveys

KW - humans

KW - life expectancy

KW - life style

KW - male

KW - middle aged

KW - models, statistical

KW - prospective studies

KW - quality-adjusted life years

KW - risk reduction behavior

KW - smoking

KW - surveys and questionnaires

KW - vegetables

U2 - 10.1093/ageing/afr058

DO - 10.1093/ageing/afr058

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C2 - 21616956

SN - 0002-0729

VL - 40

SP - 589

EP - 955

JO - Age and Ageing

JF - Age and Ageing

IS - 5

ER -

Lifestyle behaviours and quality-adjusted life years in middle and older age

Abstract

Keywords

UN SDGs

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