Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer

R M L Warren, C Hayes, Fiona Jane Gilbert, Advisory Grp UK

Research output: Contribution to journalLiterature review

18 Citations (Scopus)

Abstract

The UK study of screening for breast cancer compares mammography and dynamic contrast enhanced MRI of the breast in women at high genetic risk of developing cancer. Owing to the high sensitivity of MR in the breast, it is anticipated that some lesions will be visible only on MR. A key issue for the study is how to localize these lesions for histological verification and removal. This article reviews available methods and describes the current UK expertise and recent European developments. The use of MR compatible wires and markers has been explored in a phantom. The use of these markers in vivo is demonstrated in a case imaged by MR and mammography and further discussed. The susceptibility artefacts produced on MRI, and technical properties associated with these needles, wires and markers are discussed. The clinical pathway by which these lesions will be worked up for the study, and the quality control procedures for keeping the number of such biopsies to a minimum, are described. There is an urgent need for further centres in the UK to become proficient at removing lesions found only on MRI in support of this study and other breast MRI applications. The management of these lesions must be resolved in order to realize the full potential of MRI for screening for breast cancer in women at genetic risk, and for other diagnostic applications.

Original languageEnglish
Pages (from-to)123-132
Number of pages10
JournalBritish Journal of Radiology
Volume73
Issue number866
Publication statusPublished - Feb 2000

Keywords

  • ADD-ON DEVICE
  • MAGNETIC-RESONANCE
  • GUIDED BIOPSY
  • PREOPERATIVE LOCALIZATION
  • NEEDLE LOCALIZATION
  • FREEHAND TECHNIQUE
  • EXPERIENCE
  • SYSTEM
  • THERAPY

Cite this

Warren, R. M. L., Hayes, C., Gilbert, F. J., & Advisory Grp UK (2000). Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer. British Journal of Radiology, 73(866), 123-132.

Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer. / Warren, R M L ; Hayes, C ; Gilbert, Fiona Jane; Advisory Grp UK.

In: British Journal of Radiology, Vol. 73, No. 866, 02.2000, p. 123-132.

Research output: Contribution to journalLiterature review

Warren, RML, Hayes, C, Gilbert, FJ & Advisory Grp UK 2000, 'Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer', British Journal of Radiology, vol. 73, no. 866, pp. 123-132.
Warren, R M L ; Hayes, C ; Gilbert, Fiona Jane ; Advisory Grp UK. / Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer. In: British Journal of Radiology. 2000 ; Vol. 73, No. 866. pp. 123-132.
@article{5f46bf59337647b59d112837fd2643a4,
title = "Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer",
abstract = "The UK study of screening for breast cancer compares mammography and dynamic contrast enhanced MRI of the breast in women at high genetic risk of developing cancer. Owing to the high sensitivity of MR in the breast, it is anticipated that some lesions will be visible only on MR. A key issue for the study is how to localize these lesions for histological verification and removal. This article reviews available methods and describes the current UK expertise and recent European developments. The use of MR compatible wires and markers has been explored in a phantom. The use of these markers in vivo is demonstrated in a case imaged by MR and mammography and further discussed. The susceptibility artefacts produced on MRI, and technical properties associated with these needles, wires and markers are discussed. The clinical pathway by which these lesions will be worked up for the study, and the quality control procedures for keeping the number of such biopsies to a minimum, are described. There is an urgent need for further centres in the UK to become proficient at removing lesions found only on MRI in support of this study and other breast MRI applications. The management of these lesions must be resolved in order to realize the full potential of MRI for screening for breast cancer in women at genetic risk, and for other diagnostic applications.",
keywords = "ADD-ON DEVICE, MAGNETIC-RESONANCE, GUIDED BIOPSY, PREOPERATIVE LOCALIZATION, NEEDLE LOCALIZATION, FREEHAND TECHNIQUE, EXPERIENCE, SYSTEM, THERAPY",
author = "Warren, {R M L} and C Hayes and Gilbert, {Fiona Jane} and {Advisory Grp UK}",
year = "2000",
month = "2",
language = "English",
volume = "73",
pages = "123--132",
journal = "British Journal of Radiology",
issn = "0007-1285",
publisher = "British Institute of Radiology",
number = "866",

}

TY - JOUR

T1 - Localization of breast lesions shown only on MRI - a review for the UK study of MRI screening for breast cancer

AU - Warren, R M L

AU - Hayes, C

AU - Gilbert, Fiona Jane

AU - Advisory Grp UK

PY - 2000/2

Y1 - 2000/2

N2 - The UK study of screening for breast cancer compares mammography and dynamic contrast enhanced MRI of the breast in women at high genetic risk of developing cancer. Owing to the high sensitivity of MR in the breast, it is anticipated that some lesions will be visible only on MR. A key issue for the study is how to localize these lesions for histological verification and removal. This article reviews available methods and describes the current UK expertise and recent European developments. The use of MR compatible wires and markers has been explored in a phantom. The use of these markers in vivo is demonstrated in a case imaged by MR and mammography and further discussed. The susceptibility artefacts produced on MRI, and technical properties associated with these needles, wires and markers are discussed. The clinical pathway by which these lesions will be worked up for the study, and the quality control procedures for keeping the number of such biopsies to a minimum, are described. There is an urgent need for further centres in the UK to become proficient at removing lesions found only on MRI in support of this study and other breast MRI applications. The management of these lesions must be resolved in order to realize the full potential of MRI for screening for breast cancer in women at genetic risk, and for other diagnostic applications.

AB - The UK study of screening for breast cancer compares mammography and dynamic contrast enhanced MRI of the breast in women at high genetic risk of developing cancer. Owing to the high sensitivity of MR in the breast, it is anticipated that some lesions will be visible only on MR. A key issue for the study is how to localize these lesions for histological verification and removal. This article reviews available methods and describes the current UK expertise and recent European developments. The use of MR compatible wires and markers has been explored in a phantom. The use of these markers in vivo is demonstrated in a case imaged by MR and mammography and further discussed. The susceptibility artefacts produced on MRI, and technical properties associated with these needles, wires and markers are discussed. The clinical pathway by which these lesions will be worked up for the study, and the quality control procedures for keeping the number of such biopsies to a minimum, are described. There is an urgent need for further centres in the UK to become proficient at removing lesions found only on MRI in support of this study and other breast MRI applications. The management of these lesions must be resolved in order to realize the full potential of MRI for screening for breast cancer in women at genetic risk, and for other diagnostic applications.

KW - ADD-ON DEVICE

KW - MAGNETIC-RESONANCE

KW - GUIDED BIOPSY

KW - PREOPERATIVE LOCALIZATION

KW - NEEDLE LOCALIZATION

KW - FREEHAND TECHNIQUE

KW - EXPERIENCE

KW - SYSTEM

KW - THERAPY

M3 - Literature review

VL - 73

SP - 123

EP - 132

JO - British Journal of Radiology

JF - British Journal of Radiology

SN - 0007-1285

IS - 866

ER -