Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome

L. Macdonald, Julie Bruce, Neil William Scott, William Cairns Stewart Smith, W. A. Chambers

Research output: Contribution to journalArticle

196 Citations (Scopus)

Abstract

Post- mastectomy pain syndrome ( PMPS) is a recognised complication of breast surgery although little is known about the long- term outcome of this chronic pain condition. In 1996, Smith et al identified a prevalence rate of PMPS of 43% among 408 women in the Grampian Region, Northeast Scotland. The aim of this study was to assess long- term outcome at 7 - 12 years postoperatively in this cohort of women, to describe the natural history of PMPS and impact of pain upon quality of life. Chronic pain and quality of life were assessed using the McGill Pain Questionnaire ( MPQ) and Short Form- 36 ( SF- 36). Of 175 women reporting PMPS in 1996, 138 were eligible for questionnaire follow- up in 2002. Mean time since surgery was 9 years ( s. d. 1.8 years). A response rate of 82% ( 113 out of 138) was achieved; 59 out of 113 ( 52%) women reported continued PMPS and 54 out of 113 ( 48%) women reported their PMPS had resolved since the previous survey in 1996. Quality of life scores were significantly lower in women with persistent PMPS compared to those women whose pain had resolved. However, for women with persistent PMPS, SF- 36 scores had improved over time. Risk factors for persistent PMPS included younger age and heavier weight. This study found that, of women reporting PMPS in 1996, half of those surveyed in 2002 continued to experience PMPS at a mean of 9 years after surgery.

Original languageEnglish
Pages (from-to)225-230
Number of pages5
JournalBritish Journal of Cancer
Volume92
Issue number2
DOIs
Publication statusPublished - Jan 2005

Keywords

  • breast cancer
  • mastectomy
  • post mastectomy pain
  • chronic pain
  • SF-36 HEALTH SURVEY
  • NEUROPATHIC PAIN
  • INTERCOSTOBRACHIAL NERVE
  • SHORT-FORM
  • QUESTIONNAIRE
  • SURGERY
  • PREVALENCE
  • UPDATE
  • COHORT

Cite this

Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome. / Macdonald, L.; Bruce, Julie; Scott, Neil William; Smith, William Cairns Stewart; Chambers, W. A.

In: British Journal of Cancer, Vol. 92, No. 2, 01.2005, p. 225-230.

Research output: Contribution to journalArticle

@article{1a35b33f5df0460b9b05be4ab1cb51e0,
title = "Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome",
abstract = "Post- mastectomy pain syndrome ( PMPS) is a recognised complication of breast surgery although little is known about the long- term outcome of this chronic pain condition. In 1996, Smith et al identified a prevalence rate of PMPS of 43{\%} among 408 women in the Grampian Region, Northeast Scotland. The aim of this study was to assess long- term outcome at 7 - 12 years postoperatively in this cohort of women, to describe the natural history of PMPS and impact of pain upon quality of life. Chronic pain and quality of life were assessed using the McGill Pain Questionnaire ( MPQ) and Short Form- 36 ( SF- 36). Of 175 women reporting PMPS in 1996, 138 were eligible for questionnaire follow- up in 2002. Mean time since surgery was 9 years ( s. d. 1.8 years). A response rate of 82{\%} ( 113 out of 138) was achieved; 59 out of 113 ( 52{\%}) women reported continued PMPS and 54 out of 113 ( 48{\%}) women reported their PMPS had resolved since the previous survey in 1996. Quality of life scores were significantly lower in women with persistent PMPS compared to those women whose pain had resolved. However, for women with persistent PMPS, SF- 36 scores had improved over time. Risk factors for persistent PMPS included younger age and heavier weight. This study found that, of women reporting PMPS in 1996, half of those surveyed in 2002 continued to experience PMPS at a mean of 9 years after surgery.",
keywords = "breast cancer, mastectomy, post mastectomy pain, chronic pain, SF-36 HEALTH SURVEY, NEUROPATHIC PAIN, INTERCOSTOBRACHIAL NERVE, SHORT-FORM, QUESTIONNAIRE, SURGERY, PREVALENCE, UPDATE, COHORT",
author = "L. Macdonald and Julie Bruce and Scott, {Neil William} and Smith, {William Cairns Stewart} and Chambers, {W. A.}",
year = "2005",
month = "1",
doi = "10.1038/SJ.BJC.6602304",
language = "English",
volume = "92",
pages = "225--230",
journal = "British Journal of Cancer",
issn = "0007-0920",
publisher = "Nature Publishing Group",
number = "2",

}

TY - JOUR

T1 - Long-term follow-up of breast cancer survivors with post-mastectomy pain syndrome

AU - Macdonald, L.

AU - Bruce, Julie

AU - Scott, Neil William

AU - Smith, William Cairns Stewart

AU - Chambers, W. A.

PY - 2005/1

Y1 - 2005/1

N2 - Post- mastectomy pain syndrome ( PMPS) is a recognised complication of breast surgery although little is known about the long- term outcome of this chronic pain condition. In 1996, Smith et al identified a prevalence rate of PMPS of 43% among 408 women in the Grampian Region, Northeast Scotland. The aim of this study was to assess long- term outcome at 7 - 12 years postoperatively in this cohort of women, to describe the natural history of PMPS and impact of pain upon quality of life. Chronic pain and quality of life were assessed using the McGill Pain Questionnaire ( MPQ) and Short Form- 36 ( SF- 36). Of 175 women reporting PMPS in 1996, 138 were eligible for questionnaire follow- up in 2002. Mean time since surgery was 9 years ( s. d. 1.8 years). A response rate of 82% ( 113 out of 138) was achieved; 59 out of 113 ( 52%) women reported continued PMPS and 54 out of 113 ( 48%) women reported their PMPS had resolved since the previous survey in 1996. Quality of life scores were significantly lower in women with persistent PMPS compared to those women whose pain had resolved. However, for women with persistent PMPS, SF- 36 scores had improved over time. Risk factors for persistent PMPS included younger age and heavier weight. This study found that, of women reporting PMPS in 1996, half of those surveyed in 2002 continued to experience PMPS at a mean of 9 years after surgery.

AB - Post- mastectomy pain syndrome ( PMPS) is a recognised complication of breast surgery although little is known about the long- term outcome of this chronic pain condition. In 1996, Smith et al identified a prevalence rate of PMPS of 43% among 408 women in the Grampian Region, Northeast Scotland. The aim of this study was to assess long- term outcome at 7 - 12 years postoperatively in this cohort of women, to describe the natural history of PMPS and impact of pain upon quality of life. Chronic pain and quality of life were assessed using the McGill Pain Questionnaire ( MPQ) and Short Form- 36 ( SF- 36). Of 175 women reporting PMPS in 1996, 138 were eligible for questionnaire follow- up in 2002. Mean time since surgery was 9 years ( s. d. 1.8 years). A response rate of 82% ( 113 out of 138) was achieved; 59 out of 113 ( 52%) women reported continued PMPS and 54 out of 113 ( 48%) women reported their PMPS had resolved since the previous survey in 1996. Quality of life scores were significantly lower in women with persistent PMPS compared to those women whose pain had resolved. However, for women with persistent PMPS, SF- 36 scores had improved over time. Risk factors for persistent PMPS included younger age and heavier weight. This study found that, of women reporting PMPS in 1996, half of those surveyed in 2002 continued to experience PMPS at a mean of 9 years after surgery.

KW - breast cancer

KW - mastectomy

KW - post mastectomy pain

KW - chronic pain

KW - SF-36 HEALTH SURVEY

KW - NEUROPATHIC PAIN

KW - INTERCOSTOBRACHIAL NERVE

KW - SHORT-FORM

KW - QUESTIONNAIRE

KW - SURGERY

KW - PREVALENCE

KW - UPDATE

KW - COHORT

U2 - 10.1038/SJ.BJC.6602304

DO - 10.1038/SJ.BJC.6602304

M3 - Article

VL - 92

SP - 225

EP - 230

JO - British Journal of Cancer

JF - British Journal of Cancer

SN - 0007-0920

IS - 2

ER -