Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study

Kyu Yean Kim; Marc Miravitlles; Pawel Sliwinski; Richard Costello; Victoria Carter; Jessica Tan; Therese Sophie Lapperre; Bernardino Alcazar; Caroline Gouder; Cristina Esquinas; Juan Luis García-Rivero; Anu Kemppinen; Augustine Tee; Miguel Roman-Rodríguez; Juan José Soler-Cataluña; David Price; Chin Kook Rhee

doi:10.2147/COPD.S208245

Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study

Kyu Yean Kim, Marc Miravitlles, Pawel Sliwinski, Richard Costello, Victoria Carter, Jessica Tan, Therese Sophie Lapperre, Bernardino Alcazar, Caroline Gouder, Cristina Esquinas, Juan Luis García-Rivero, Anu Kemppinen, Augustine Tee, Miguel Roman-Rodríguez, Juan José Soler-Cataluña, David Price, Chin Kook Rhee

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

7 Downloads (Pure)

Abstract

We aimed to compare clinical characteristics between Asian and Western chronic obstructive pulmonary disease (COPD) patients. This was a sub-analysis of an international, multicenter, prospective cohort study. Asian patients were enrolled in Singapore and South Korea. Western patients were enrolled in Spain, Poland, Ireland, the United Kingdom, and Malta. A total of 349 patients were analyzed. Among them, 110 (32%) patients were Asian and 239 (68%) Western. Male sex was more predominant in Asian than in Western (95% versus 63%, respectively; P<0.01). Body mass index was significantly lower in Asian (23.5 versus 27.1; P<0.01). The proportion of patients with a history of exacerbation was lower in Asian (12% versus 64%; P<0.01). Although patients were enrolled by same inclusion criteria, there were several differences between Asian and Western COPD patients. Our study has shown unbiased real-world differences between Asian and Western COPD patients. Since prospective follow-up study is currently ongoing, the result of this study can be fundamental base of future analysis.

Original language	English
Pages (from-to)	1595-1601
Number of pages	7
Journal	International journal of chronic obstructive pulmonary disease
Volume	14
DOIs	https://doi.org/10.2147/COPD.S208245
Publication status	Published - 25 Jul 2019

Bibliographical note

The study was designed and coordinated by the Respiratory Effectiveness Group (REG; www.effectivenessevaluation.org; Cambridge, UK) and delivered by Optimum Patient Care (OPC; www.optimumpatientcare.org). The following investigators participated in the study: Spain: Marc Miravitlles, Cristina Esquinas, Miriam Barrecheguren, Alexa Nuñez, Hospital Universitari Vall d’Hebron, Barcelona. Bernardino Alcazar, Hospital de Alta Resolución de Loja. Juan Luis García-Rivero, Karina Hueso, Hospital Comarcal de Laredo, Cantabria. Miguel Roman-Rodríguez, Primary Health-care Center Son Pisà. IB-Salut. Palma de Mallorca. Poland: Pawel Sliwinsk Sliwinski, Katarzyna Iwan, Jacek Kolakowski, Institute of Tuberculosis and Lung Diseases, Warsaw. Korea: Chin Kook Rhee, Esther Ahn, St Mary’s Hospital. Seoul. Singapore: Jessica Tan, Therese Lapperre, Karen Tan Li Leng, Nicole Chia, Ong Thun How, Syifa Binte Shamsuddin, Sherine Lim Shu Gim, Yap Chwee Bee, Soh Rui Ya, Singapore General Hospital. Augustine Tee, Jun Jie Yan, Samuel Hong, William Tan, Jessica Tan, Changi General Hospital. UK: Victoria Carter, Latife Hardaker, Andrew McLaughlin, Optimum Patient Care, Cambridge. Malta: Caroline Gouder, Mater Dei Hospital. Ireland: Richard W Costello, Royal College of Surgeons. Dublin. The study was funded by an unrestricted grant from Novartis AG.

Keywords

COPD
Asian
Western

Access to Document

10.2147/COPD.S208245Licence: CC BY-NC

Price_ComparisonOfClinical_VOR
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms. https://creativecommons.org/licenses/by-nc/3.0/
Final published version, 234 KBLicence: CC BY-NC

Cite this

Kim, K. Y., Miravitlles, M., Sliwinski, P., Costello, R., Carter, V., Tan, J., Lapperre, T. S., Alcazar, B., Gouder, C., Esquinas, C., García-Rivero, J. L., Kemppinen, A., Tee, A., Roman-Rodríguez, M., Soler-Cataluña, J. J., Price, D., & Rhee, C. K. (2019). Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study. International journal of chronic obstructive pulmonary disease , 14, 1595-1601. https://doi.org/10.2147/COPD.S208245

Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study. / Kim, Kyu Yean; Miravitlles, Marc; Sliwinski, Pawel et al.
In: International journal of chronic obstructive pulmonary disease , Vol. 14, 25.07.2019, p. 1595-1601.

Research output: Contribution to journal › Article › peer-review

Kim, KY, Miravitlles, M, Sliwinski, P, Costello, R, Carter, V, Tan, J, Lapperre, TS, Alcazar, B, Gouder, C, Esquinas, C, García-Rivero, JL, Kemppinen, A, Tee, A, Roman-Rodríguez, M, Soler-Cataluña, JJ, Price, D & Rhee, CK 2019, 'Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study', International journal of chronic obstructive pulmonary disease , vol. 14, pp. 1595-1601. https://doi.org/10.2147/COPD.S208245

@article{7bfe42f1b76b4ef69a73e2939cb10307,

title = "Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study",

abstract = "We aimed to compare clinical characteristics between Asian and Western chronic obstructive pulmonary disease (COPD) patients. This was a sub-analysis of an international, multicenter, prospective cohort study. Asian patients were enrolled in Singapore and South Korea. Western patients were enrolled in Spain, Poland, Ireland, the United Kingdom, and Malta. A total of 349 patients were analyzed. Among them, 110 (32%) patients were Asian and 239 (68%) Western. Male sex was more predominant in Asian than in Western (95% versus 63%, respectively; P<0.01). Body mass index was significantly lower in Asian (23.5 versus 27.1; P<0.01). The proportion of patients with a history of exacerbation was lower in Asian (12% versus 64%; P<0.01). Although patients were enrolled by same inclusion criteria, there were several differences between Asian and Western COPD patients. Our study has shown unbiased real-world differences between Asian and Western COPD patients. Since prospective follow-up study is currently ongoing, the result of this study can be fundamental base of future analysis.",

keywords = "COPD, Asian, Western",

author = "Kim, {Kyu Yean} and Marc Miravitlles and Pawel Sliwinski and Richard Costello and Victoria Carter and Jessica Tan and Lapperre, {Therese Sophie} and Bernardino Alcazar and Caroline Gouder and Cristina Esquinas and Garc{\'i}a-Rivero, {Juan Luis} and Anu Kemppinen and Augustine Tee and Miguel Roman-Rodr{\'i}guez and Soler-Catalu{\~n}a, {Juan Jos{\'e}} and David Price and Rhee, {Chin Kook}",

note = "The study was designed and coordinated by the Respiratory Effectiveness Group (REG; www.effectivenessevaluation.org; Cambridge, UK) and delivered by Optimum Patient Care (OPC; www.optimumpatientcare.org). The following investigators participated in the study: Spain: Marc Miravitlles, Cristina Esquinas, Miriam Barrecheguren, Alexa Nu{\~n}ez, Hospital Universitari Vall d{\textquoteright}Hebron, Barcelona. Bernardino Alcazar, Hospital de Alta Resoluci{\'o}n de Loja. Juan Luis Garc{\'i}a-Rivero, Karina Hueso, Hospital Comarcal de Laredo, Cantabria. Miguel Roman-Rodr{\'i}guez, Primary Health-care Center Son Pis{\`a}. IB-Salut. Palma de Mallorca. Poland: Pawel Sliwinsk Sliwinski, Katarzyna Iwan, Jacek Kolakowski, Institute of Tuberculosis and Lung Diseases, Warsaw. Korea: Chin Kook Rhee, Esther Ahn, St Mary{\textquoteright}s Hospital. Seoul. Singapore: Jessica Tan, Therese Lapperre, Karen Tan Li Leng, Nicole Chia, Ong Thun How, Syifa Binte Shamsuddin, Sherine Lim Shu Gim, Yap Chwee Bee, Soh Rui Ya, Singapore General Hospital. Augustine Tee, Jun Jie Yan, Samuel Hong, William Tan, Jessica Tan, Changi General Hospital. UK: Victoria Carter, Latife Hardaker, Andrew McLaughlin, Optimum Patient Care, Cambridge. Malta: Caroline Gouder, Mater Dei Hospital. Ireland: Richard W Costello, Royal College of Surgeons. Dublin. The study was funded by an unrestricted grant from Novartis AG.",

year = "2019",

month = jul,

day = "25",

doi = "10.2147/COPD.S208245",

language = "English",

volume = "14",

pages = "1595--1601",

journal = "International journal of chronic obstructive pulmonary disease ",

issn = "1176-9106",

publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study

AU - Kim, Kyu Yean

AU - Miravitlles, Marc

AU - Sliwinski, Pawel

AU - Costello, Richard

AU - Carter, Victoria

AU - Tan, Jessica

AU - Lapperre, Therese Sophie

AU - Alcazar, Bernardino

AU - Gouder, Caroline

AU - Esquinas, Cristina

AU - García-Rivero, Juan Luis

AU - Kemppinen, Anu

AU - Tee, Augustine

AU - Roman-Rodríguez, Miguel

AU - Soler-Cataluña, Juan José

AU - Price, David

AU - Rhee, Chin Kook

N1 - The study was designed and coordinated by the Respiratory Effectiveness Group (REG; www.effectivenessevaluation.org; Cambridge, UK) and delivered by Optimum Patient Care (OPC; www.optimumpatientcare.org). The following investigators participated in the study: Spain: Marc Miravitlles, Cristina Esquinas, Miriam Barrecheguren, Alexa Nuñez, Hospital Universitari Vall d’Hebron, Barcelona. Bernardino Alcazar, Hospital de Alta Resolución de Loja. Juan Luis García-Rivero, Karina Hueso, Hospital Comarcal de Laredo, Cantabria. Miguel Roman-Rodríguez, Primary Health-care Center Son Pisà. IB-Salut. Palma de Mallorca. Poland: Pawel Sliwinsk Sliwinski, Katarzyna Iwan, Jacek Kolakowski, Institute of Tuberculosis and Lung Diseases, Warsaw. Korea: Chin Kook Rhee, Esther Ahn, St Mary’s Hospital. Seoul. Singapore: Jessica Tan, Therese Lapperre, Karen Tan Li Leng, Nicole Chia, Ong Thun How, Syifa Binte Shamsuddin, Sherine Lim Shu Gim, Yap Chwee Bee, Soh Rui Ya, Singapore General Hospital. Augustine Tee, Jun Jie Yan, Samuel Hong, William Tan, Jessica Tan, Changi General Hospital. UK: Victoria Carter, Latife Hardaker, Andrew McLaughlin, Optimum Patient Care, Cambridge. Malta: Caroline Gouder, Mater Dei Hospital. Ireland: Richard W Costello, Royal College of Surgeons. Dublin. The study was funded by an unrestricted grant from Novartis AG.

PY - 2019/7/25

Y1 - 2019/7/25

N2 - We aimed to compare clinical characteristics between Asian and Western chronic obstructive pulmonary disease (COPD) patients. This was a sub-analysis of an international, multicenter, prospective cohort study. Asian patients were enrolled in Singapore and South Korea. Western patients were enrolled in Spain, Poland, Ireland, the United Kingdom, and Malta. A total of 349 patients were analyzed. Among them, 110 (32%) patients were Asian and 239 (68%) Western. Male sex was more predominant in Asian than in Western (95% versus 63%, respectively; P<0.01). Body mass index was significantly lower in Asian (23.5 versus 27.1; P<0.01). The proportion of patients with a history of exacerbation was lower in Asian (12% versus 64%; P<0.01). Although patients were enrolled by same inclusion criteria, there were several differences between Asian and Western COPD patients. Our study has shown unbiased real-world differences between Asian and Western COPD patients. Since prospective follow-up study is currently ongoing, the result of this study can be fundamental base of future analysis.

AB - We aimed to compare clinical characteristics between Asian and Western chronic obstructive pulmonary disease (COPD) patients. This was a sub-analysis of an international, multicenter, prospective cohort study. Asian patients were enrolled in Singapore and South Korea. Western patients were enrolled in Spain, Poland, Ireland, the United Kingdom, and Malta. A total of 349 patients were analyzed. Among them, 110 (32%) patients were Asian and 239 (68%) Western. Male sex was more predominant in Asian than in Western (95% versus 63%, respectively; P<0.01). Body mass index was significantly lower in Asian (23.5 versus 27.1; P<0.01). The proportion of patients with a history of exacerbation was lower in Asian (12% versus 64%; P<0.01). Although patients were enrolled by same inclusion criteria, there were several differences between Asian and Western COPD patients. Our study has shown unbiased real-world differences between Asian and Western COPD patients. Since prospective follow-up study is currently ongoing, the result of this study can be fundamental base of future analysis.

KW - COPD

KW - Asian

KW - Western

U2 - 10.2147/COPD.S208245

DO - 10.2147/COPD.S208245

M3 - Article

C2 - 31440042

SN - 1176-9106

VL - 14

SP - 1595

EP - 1601

JO - International journal of chronic obstructive pulmonary disease

JF - International journal of chronic obstructive pulmonary disease

ER -

Comparison of clinical baseline characteristics between Asian and Western COPD patients in a prospective, international, multicenter study

Abstract

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this